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Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

Flutamide works better than finasteride for hirsutism, and combining both is slightly better but not much.

Low-dose finasteride effectively reduces hirsutism without serious side-effects.

The enzyme PST is found in developing human kidneys and helps with detoxification and development.

Itraconazole helps improve tough skin infections but may not prevent them from coming back.

Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Hair loss in postmenopausal woman caused by ovarian issue.

Cimetidine did not reduce hair growth in women with hirsutism.

The document concludes that more research is needed to fully understand the causes of PCOS.

Chronic scalp pain in trichodynia involves both body-wide and localized increased pain sensitivity.

The study suggests certain ACE gene variations are more common in women with PCOS and may be linked to increased insulin resistance.

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

The document suggests various treatments for PCOS, including medication for menstrual issues, insulin resistance, and excess hair, as well as fertility treatments, while highlighting the need for personalized care and lifestyle changes.

Stress hormones like cortisol may trigger psoriasis flare-ups.

New compounds can block testosterone effects in rats and might help treat conditions like prostate cancer and acne.

Eating a balanced diet with specific nutrients is important for menopausal women to manage hair loss.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Women with polycystic ovary syndrome have a higher risk of certain fractures.

Blood tests are needed to confirm high male hormone levels in women with PCOS, as physical signs alone are not reliable.

New treatments for excessive hair growth in women include insulin modulators and enzyme inhibitors.

Most hirsutism patients had idiopathic hirsutism or PCOS, with hormonal imbalances and signs like acne and irregular periods.

Stopping isoniazid can reverse hair loss caused by the drug.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

Androgen receptors found in monkey scalps, similar to humans, affect hair growth.

A postmenopausal woman's hirsutism and high testosterone levels improved after surgery for an ovarian tumor not seen on ultrasound.

Oral isotretinoin was recommended for a 21-year-old woman with severe acne.