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Diagnosing PCOS in teenagers should focus on signs of excess male hormones and not rely solely on ovarian ultrasound or irregular periods, and should be reassessed in adulthood.

Mutations in certain receptors can cause diseases and offer new treatment options.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Hair regrowth slows with age and can be affected by treatments that change enzyme activity in the skin.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Laser and light treatments can effectively remove hair long-term.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.

The document concludes that veterinary dermatologists need more experience and a better approach to treating skin diseases in nonhuman primates.

Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

An mFG score of 7 or higher indicates hirsutism in Filipino women, often linked to higher free testosterone levels.

Family members of North Indian women with PCOS have a high rate of metabolic syndrome.

Birth control pills help treat skin and hair growth problems linked to high male hormone levels.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Acne is an important sign of androgen excess disorders in women.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Higher hs-CRP levels in Indian adolescent women with PCOS are more related to BMI than PCOS itself.

Looking at skin can help find and treat serious diseases early.

The document reports the first Brazilian case of a girl with Becker nevus syndrome, characterized by skin changes, breast underdevelopment, and scoliosis.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.

Hair diseases can have psychological effects and should be treated with a combination of psychosomatic care, therapy, and medication.

Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.