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The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The Rotterdam Study aims to understand various diseases in older adults.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Some treatments can help with a hair loss condition called alopecia areata, but none ensure lasting results; choices depend on the person, with JAK inhibitors showing promise for severe cases.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Antiandrogens are somewhat effective in reducing excessive hair growth in women.

Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Dextran sulfate was found to be toxic and ineffective for treating HIV.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Finasteride effectively treats baldness but may cause sexual side effects.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.