68 citations,
January 2022 in “International Journal of Molecular Sciences” PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.
58 citations,
March 2011 in “Pflügers Archiv für die gesamte Physiologie des Menschen und der Tiere/Pflügers Archiv” Hormones and signaling pathways control sebaceous gland function and could help treat acne.
56 citations,
November 2007 in “Molecular and cellular endocrinology” Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.
55 citations,
May 2019 in “Journal of Endocrinology” Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
35 citations,
October 2011 in “Medicine and science in sports and exercise” Muscles can make their own androgens, which may help muscle growth.
25 citations,
June 2017 in “Neuropharmacology” Increasing TSPO in the brain reduces anxiety and depression.
24 citations,
April 2021 in “BMC women's health” High BMI worsens hair growth in women with PCOS.
19 citations,
March 2022 in “International Journal of Environmental Research and Public Health” Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.
19 citations,
December 2021 in “Endocrine Reviews” There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.
18 citations,
October 2017 in “PLOS ONE” The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.
16 citations,
November 2018 in “The journal of pain/Journal of pain” 14,15-EET may help reduce poststroke pain by affecting certain brain proteins.
16 citations,
January 2014 in “Obesity surgery” Vertical sleeve gastrectomy improved metabolism, behavior, and reproduction in obese rats with PCOS.
12 citations,
July 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” Men with hormonal imbalances similar to PCOS may have increased risk of metabolic and heart diseases.
11 citations,
April 2019 in “Bioscience Reports” Certain genetic variations in the RAB5B gene are linked to a higher risk of polycystic ovary syndrome in Chinese Han women.
6 citations,
January 2019 in “F1000Research” High triglyceride levels are a key factor affecting testosterone levels in women with PCOS.
4 citations,
August 2021 in “Biomedicine & Pharmacotherapy” 5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.
3 citations,
October 2023 in “Cosmetics” Healthy lifestyle changes can significantly improve skin health as you age.
3 citations,
May 2023 in “Biomedicines” PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.
3 citations,
November 2021 in “IntechOpen eBooks” The testes produce important hormones like testosterone and others that play key roles in male body functions.
2 citations,
January 2023 in “Pharmaceuticals” Sex and sex hormones can affect brain inflammation in Parkinson's disease, with male mice being more affected and female mice showing a protective effect.
1 citations,
November 2023 in “Journal of ovarian research” Agaricus subrufescens improves ovarian function and biochemical health in rats with PCOS.
1 citations,
July 2023 in “F&S Reviews” Some common medications may harm male fertility by affecting hormones, sperm production, and sexual function.
1 citations,
January 2023 in “BMC Women's Health” Polycystic Ovary Syndrome (PCOS) was found in 3.86% of tenth-grade girls in Guangzhou, China, with higher rates in overweight and obese girls, suggesting diagnosis should focus on hyperandrogenemia.
1 citations,
January 2023 in “Metabolites” Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.
1 citations,
May 2021 in “International Journal Of Medical Science And Clinical Invention” Women with PCOS may have a higher risk of severe COVID-19 due to hormonal imbalances and vitamin D deficiency.
1 citations,
January 2020 in “Bioscience Reports” Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.
September 2024 in “Medicina” Certain gene variations may protect against skin issues and oxidative stress in women with PCOS.
May 2024 in “Brain disorders” Agmatine may help reduce seizures linked to hormone changes in female rats.
April 2024 in “Journal of clinical medicine” Classical PCOS types A and B are most common and linked to higher health risks.
February 2024 in “ACS Omega” The Shen Bai Hair Growing Decoction may help treat hair loss by promoting hair growth and reducing inflammation.