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Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

A 12-year-old girl with very high testosterone and insulin resistance improved with birth control pills, suggesting PCOS can cause high testosterone without tumors.

An unusual growth of Leydig cells in a woman's ovaries caused her excessive hair growth, which was treated successfully with surgery.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Most women lack knowledge about androgens and their excess symptoms.

A single steroid injection can cause serious side effects like Cushing Syndrome.

Insulinomas and adrenocortical tumors are common in older ferrets, diagnosed with blood tests and ultrasounds, and treated with medications or surgery.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.

A man with X-ALD improved after treatment, highlighting the need to consider X-ALD in similar patients and test their relatives.

People with Parkinson's disease have higher levels of cortisone in their hair, which may indicate chronic stress hormone dysfunction.

The case highlights the complexity of diagnosing high testosterone in older women and the need for thorough testing.

PCOS may increase the risk of mental health issues like depression and anxiety.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

A woman had a rare liver tumor causing male-like physical changes, highlighting the need for thorough checks when such symptoms appear.

Hair loss can be an early sign of HIV infection.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

Adrenalectomy boosts hair growth and melanin in black rats, even with vitamin B¹ deficiency.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

Oral isotretinoin was recommended for a 21-year-old woman with severe acne.

Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.

Testosterone replacement can help menopausal women with various symptoms, but should be used carefully and is not yet officially licensed in the UK for women.

Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.

Treating hyperprolactinemia can help manage PCOS symptoms.

The document says that early treatment of Acne Vulgaris is important to prevent scarring and that adult onset acne is common in women, often due to hormonal imbalances.

Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.