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Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

Women with PCOS are more likely to have insulin resistance and obesity, especially those with the most severe type I PCOS.

Flutamide effectively treats female pattern hair loss with low doses showing good liver tolerance.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

Finasteride and CPA-EE2 equally reduce hirsutism, but affect hormone levels differently.

Weight loss and metformin don't significantly change vaspin levels in women with PCOS.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

Male rats grow hair faster than females, and certain hormones can slow or slightly increase hair growth, but not significantly beyond natural rates.

Cyproterone acetate reduced hair growth in most hirsute females and made hair softer, thinner, and lighter.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.

Family members of North Indian women with PCOS have a high rate of metabolic syndrome.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.

The document says menstruation is important for women's health, discusses menstrual disorders, and suggests personalized treatment options.

Eating less starch and dairy helped overweight women with PCOS lose weight and improve symptoms.

Cimetidine did not reduce hair growth in women with hirsutism.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.