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A special gene region controls the re-emergence of a primitive wool type in Merino sheep, improving their wool yield and adaptability.

Targeting lipid metabolism can help treat advanced, resistant cancers.

Hormone replacement therapy may lower the risk of severe COVID-19 outcomes in non-immunosuppressed people and male organ transplant recipients.

RORA may help regulate hair growth by affecting hair follicle stem cells.

Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.

Th22 cells are essential for Tβ15-induced hair growth in mice.

Zinc/silicon-infused hydrogel helps regenerate hair follicles.

Bead-jet printing of stem cells improves muscle and hair regeneration.

Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Hair follicles help attract immune cells to the skin during stress.

Free fatty acids in sebum boost skin's defense against acne by increasing antimicrobial peptides.

Intestinal intraepithelial lymphocytes are crucial for gut immunity and maintaining the mucosal barrier.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Targeting TGFβ can improve skin immunity in older people.

Tyrosine kinases are important in skin autoimmune diseases and could be targets for new treatments.

Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.

Alopecia areata may be treated by restoring hair follicle immune privilege and adjusting immune responses.

Heavily hunted wolves have higher stress and reproductive hormone levels.

SkQ1 antioxidant improved health and lifespan in mice.

Alopecia areata can be triggered by specific immune cells without genetic or environmental factors.

Surgical robots have improved but still can't perform tasks or make decisions on their own.

Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.

Probiotics show promise for health benefits but need more research to understand how they work.

New insights into the causes and treatments for the autoimmune hair loss condition Alopecia areata have been made.

The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.