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The hydrogel helps heal seawater-immersed wounds by reducing infection and inflammation.

This meta-analysis found that ADSC-Exo therapy can enhance healing in both general and diabetic wounds by promoting neovascularization, improving epithelization and collagen fiber deposition, and reducing scar formation, suggesting significant potential for clinical and research applications.

In a rat skin wound model, this study observed that a composite dressing using chitosan hydrogel and exosomes derived from adipose mesenchymal stem cells enhanced wound healing by promoting collagen deposition, angiogenesis, and regeneration of hair follicle structures.

This single-patient case study reported promising results for severe, corticosteroid-resistant alopecia areata, with treatment using exosomes derived from mesenchymal stromal cells leading to almost complete hair regrowth in 12 weeks and favorable changes in inflammatory markers, suggesting potential for further investigation.

This study found that exosome-incorporated human amniotic membrane scaffolds notably enhanced diabetic skin wound healing in mice, suggesting potential applications for ADSC-derived exosomes in clinical settings.

This study found that adipose-derived stem cell exosomes promoted hair follicle regeneration in mice, resulting in a higher number of regenerated hairs and follicles compared to the control group.

This study observed that exosomes from adipose-derived stem cells promoted hair growth by enhancing dermal papilla cell proliferation and activating signaling pathways, suggesting potential for treating immune-mediated alopecia.

This review highlights that exosomes from adipose-derived stem cells, particularly those enriched with circ-Ash1l, can inhibit ferroptosis and reduce UVB-induced skin aging by delivering GPX4-promoting signals to damaged cells, thus offering a potential regenerative therapy for photoaged skin.

This study using human and animal models found that adipose-derived stem cell exosomes promoted hair growth and counteracted dihydrotestosterone's inhibitory effects, suggesting potential therapeutic applications for androgenetic alopecia.

This study found that adipose-derived stem cell exosomes increased dermal papilla cell proliferation and elevated proteins linked to hair follicle inducibility in vitro.

This study found that exosomes from adipose mesenchymal stromal cells, particularly those carrying miR-122-5p, may enhance hair follicle regeneration in androgenic alopecia by targeting the TGF-β/SMAD3 axis.

This study discovered that exosomes from adipose-derived mesenchymal stem cells can mitigate damage in dermal papilla cells by modulating the TGF-β1/SMAD2 signaling pathway through miRNAs miR-574-3p and miR-125a-5p, revealing potential therapeutic targets for androgenetic alopecia.

This study found that while clinical evidence is limited, early preclinical results suggest exosome treatment may enhance hair growth and warrant further research for therapeutic use in alopecia.

This review discusses the potential of secretome derived from stem cells for treating alopecia areata and reports no new clinical results; the authors suggest the need for further human trials.

This review discusses regenerative medicine approaches for treating alopecia, including mesenchymal stem cell therapies and platelet-rich plasma, but reports no new clinical results, emphasizing the need for further study.

This study found that a newly developed ultrasound-responsive hydrogel, incorporating ADSC-derived exosome nanobubbles, substantially improved wound healing in rats by enhancing skin closure, re-epithelialization, and hair follicle regeneration, while potentially reducing scar formation.

This study reported that bio-pulsed avian-derived mesenchymal stem cell extracellular vesicles significantly improved cell proliferation, wound healing, and gene expression in human skin fibroblasts and hair follicle cells.

This review examines adipose-derived stem cells as a promising therapy for alopecia but reports no new clinical results, discussing their potential mechanisms and the challenges faced in treatment development.

This review discusses autologous fat grafting in various medical procedures, emphasizing the differing effects of stromal vascular fraction and expanded adipose-derived stem cells on fat retention, but reports no new clinical results.

This review reports significant advancements in plastic surgery using stem cell therapies for aesthetic and reconstructive applications, including grafting and wound healing, though it underscores the need for continued research to address regulatory, ethical, and standardization issues.

This study observed that exosomes from adipose mesenchymal stem cells overexpressing hepatocyte growth factor significantly improved liver function and reduced fibrosis in mice with experimentally induced liver injury.

This source reviews the role of exosomes in regenerative medicine, highlighting their ability to mediate cell communication and transport biomolecules to enhance or impair biological functions, with potential applications in tissue repair and regeneration.

This review discusses the potential of endogenic and exogenous exosomes in dermatology and cutaneous aesthetics, highlighting their capacity to repair and rejuvenate skin tissue, but reports no new experimental results.

This study found that applying HHORSC exosomes may enhance the hair inductivity of dermal papilla cells, potentially improving treatments for hair loss.

This narrative review highlights the potential of autologous adipose mesenchymal stem cell-derived exosomes (AMSCs-Exos) in anti-skin aging, noting their superior biocompatibility and manufacturing advantages while stressing the need for standardized production protocols to overcome existing application challenges.

This study reviews the regenerative potential and clinical applications of exosomes derived from mesenchymal stem cells in conditions like COVID-19, alopecia, skin aging, and osteoarthritis, highlighting their role as a promising tool in regenerative medicine.

This study demonstrated that a bio-3D printed artificial skin scaffold, seeded with adipose-derived mesenchymal stem cells, showed promising wound healing properties by enhancing cell recruitment, migration, and gene expression related to tissue regeneration.

This analysis concluded that mesenchymal stem cell-derived exosome therapy may offer a promising and safe approach for hair restoration, especially in androgenetic alopecia, despite limitations in study consistency and size.

This review discusses recent advances in the therapeutic potential of exosomes for wound healing, highlighting their benefits and challenges but reports no new clinical results.

This review explores the potential for using exosomes in treating autoimmune skin diseases and promoting skin regeneration, highlighting current applications, delivery methods, and ongoing clinical trials while also identifying challenges and future research directions within dermatology.