research Assessing Dutasteride-Associated Sexual Dysfunction Using the U.S. Food and Drug Administration Adverse Event Reporting System
Dutasteride is linked to a higher chance of sexual dysfunction, especially in younger males and the elderly.
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research Prevalence of Autoimmune and Inflammatory Diseases and Mental Health Conditions Among an Alopecia Areata Cohort from a US Administrative Claims Database
People with Alopecia Areata are more likely to have autoimmune diseases, inflammatory diseases, and mental health issues like anxiety and depression.
research The Effects of Methylated Flavonoids on Depression-Like Activity and Pro-Inflammatory Cytokine Thresholds in Mice Induced by Repeated Finasteride Administration
Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.
research Analysis of the Effects of Platelet-Rich Plasma Injection on the Human Body Depending on the Site of Administration – Review Article
Platelet-rich plasma injections can help the body heal and treat conditions like hair loss, wound healing, acne scars, erectile dysfunction, and osteoarthritis, but more research is needed.
research Evaluation of Serum Ferritin, Creatinine, and Liver Enzymes in Patients with Beta-Thalassemia After Administration of Deferasirox
Deferasirox effectively reduces iron overload in ß-thalassemia patients but may cause some manageable side effects.
research The Multidimensional Assessment of Interoceptive Awareness-2 Scale: A Turkish Validity and Reliability Study in Patients Admitted to the Dermatology Outpatient Clinic
The Turkish version of the MAIA-2 Scale is valid and reliable for patients at a dermatology clinic.
research Possible Contributory and Protective Factors in Medication Associated Obstructive Sleep Apnea: Results from the US Food and Drug Administration Adverse Events Reporting System
Some drugs may increase the risk of obstructive sleep apnea, while others like certain biologics might decrease it.
research Suspected Calcinosis Cutis and Demodicosis Secondary to Exogenous Steroid Administration in a Dog with Hypoadrenocorticism
A dog developed skin issues from too many steroids, but reducing steroids and using a specific treatment fixed the problems.
research Trends in 5-Alpha Reductase Inhibitor Use Before and After the Food and Drug Administration Safety Warning
Prescriptions for 5-alpha reductase inhibitors dropped significantly after the FDA's safety warning, especially for men with benign prostatic hyperplasia.
research Study on Toxicity of Hydrocortisone 17-Butyrate 21-Propionate: Subacute Toxicity in Dogs by Percutaneous Administration
Hydrocortisone 17-butyrate 21-propionate ointment caused reversible side effects like skin issues, weight gain, and organ changes in dogs.
research Protac Degraders of Androgen Receptor-Integrated Dissolving Microneedles for Androgenetic Alopecia and Recrudescence Treatment via Single Topical Administration
A new hair loss treatment using dissolving microneedles was found to speed up hair growth and was more effective than daily use of common hair growth drugs.
research Finasteride Use Is Associated with Higher Odds of Obstructive Sleep Apnea: Results from the US Food and Drug Administration Adverse Events Reporting System
Finasteride use is linked to a higher risk of obstructive sleep apnea.
research Finasteride Use Is Associated with Higher Odds of Obstructive Sleep Apnea: Results from the US Food and Drug Administration Adverse Events Reporting System
Finasteride use is linked to a higher risk of obstructive sleep apnea.
research Tolerability of Hair Cleansing Conditioners: A Double-Blind Randomized Controlled Trial Evaluating Consumer Complaints to the U.S. Food and Drug Administration
Wen by Chaz Dean Sweet Almond Mint Cleansing Conditioner is better tolerated than salicylic acid and baby shampoos.
research Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women
The drug BAY 1158061 is safe, well-tolerated, and shows potential for treating diseases related to prolactin.
research Are Finasteride-Related Penile Curvature/Peyronie’s Disease Adverse Event Reports Worthy of Further Clinical Investigation? Disproportionality Analysis Based on Both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) Pharmacovigilance Databases
Finasteride may be linked to Peyronie’s disease, but more research is needed.
research Studies on the Disposition of Finasteride: Absorption, Distribution, and Excretion of (14C)finasteride After Single Oral or Intravenous Administration in Rats
Finasteride has different absorption and metabolism in male and female rats, with higher concentrations in certain organs and mostly excreted through feces.
research The Role of Patient and Drug-Related Factors in Oral Minoxidil and Pericardial Effusion: Analyses of Data From the United States Food and Drug Administration Adverse Event Reporting System
Oral minoxidil rarely causes pericardial effusion, especially at low doses.
research The Possible Role of Prescribing Medications in Contributing to Male-Factor Infertility: Assessment of the FDA Pharmacovigilance Database
Some medications might contribute to male infertility, with finasteride showing a high number of reports.
research Is Finasteride Intake Associated with Penile Curvature/Peyronie’s Disease? Assessment of Both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) Pharmacovigilance Databases
research A Double Blind, Randomised, Vehicle-Controlled, Safety and Tolerance Study of Topical PSK 3841 Solution at 5% Administered Twice Daily Over Four Weeks to Healthy Caucasian Males with Androgenetic Alopecia
research Response of Drs. J. E. Pope and E. H. Makela to the Article 'Depression Circumstantially Related to the Administration of Finasteride for Androgenetic Alopecia'
Authors defend finasteride-depression link, suggest detailed medical history, and call for more investigation.
research Neovascularization During Healing of Wounds Treated with Dermal Substitutes and Fibrin Glue in Nude Mice
Dermagraft and Dermalogen had a lot of granulation, while Alloderm, Integra, and ADM had good blood vessel growth for skin healing.
research Membrane Androgen Receptors May Mediate Androgen Reinforcement
Androgen self-administration might be controlled by membrane receptors, not nuclear ones.
research Impact of Anti-Androgen Therapies on COVID-19 Susceptibility: A Case-Control Study in Male Population from Two COVID-19 Regional Centers of Lombardy, Italy
Men taking 5-alpha reductase inhibitors for prostate issues may be less likely to experience severe COVID-19, but it doesn't prevent ICU admission or death.
research Proxalutamide Reduces the Rate of Hospitalization for COVID-19 Male Outpatients: A Randomized Double-Blinded Placebo-Controlled Trial
Proxalutamide significantly lowered hospital admissions for male COVID-19 patients compared to a placebo.
research Surfactants' Role in Nanovesicles Drug Delivery System
Surfactants in spanlastics improve drug delivery by making nanovesicles more flexible and stable for painless administration through the mouth.
research An Update on Antiviral Treatment of COVID-19
As of December 2021, the most effective COVID-19 treatments were monoclonal antibodies and possibly early-administered convalescent plasma, while several drugs were found ineffective or were still under evaluation.
research Vulvovaginitis Due to Bone Structure in the Vaginal Canal of a Spayed Dog: Case Report
A spayed dog with vaginal bone structures causing infection was successfully treated by removing the bones and administering medication.
research Editor's Picks January 2021
PrEP doesn't increase STI risk in high-risk men, anti-androgen drugs may lower ICU admission for male COVID-19 patients, a 3-point injection is better for crow's feet, and the 'Geriatric-8' tool could help assess frailty in older skin cancer patients.