Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, the authors reported that while deoxycholic acid effectively reduces submental fat, it can cause adverse effects such as edema, numbness, and skin necrosis, making knowledge of possible complications essential for clinicians.

This study found that using an oral contraceptive with bicalutamide significantly reduced hirsutism in women with PCOS compared to an oral contraceptive alone, although it increased total cholesterol and LDL levels.

This article reviews the role of R-spondins and their receptors in bone development and metabolism, highlighting their potential modulatory effects and clinical implications for treating bone loss diseases, but reports no new clinical results.

This study found that local androgen biosynthesis and metabolism in human sebaceous glands play a crucial role in sebum synthesis and secretion.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

This review discusses the broader roles of angiogenic factors, like VEGFs and FGFs, beyond angiogenesis, highlighting their involvement in various biological and pathological processes.

This study found that specific SHBG gene variants and haplotypes are associated with polycystic ovary syndrome, suggesting that SHBG may be a candidate gene for the condition.

This review discusses the diagnostic criteria and treatment options for adolescent polycystic ovary syndrome, highlighting ongoing debates and the need for further research, without presenting new clinical results.

This review compiles existing data on frontal fibrosing alopecia and highlights the promise of 5-alpha reductase inhibitors as a treatment option, while noting the need for clarity on its cause and progression.

This article reviews the roles of lesser-known secreted phospholipase A2 isoforms in various biological processes, such as immune suppression, metabolic regulation, epidermal hyperplasia, and male reproduction, without reporting new clinical findings.

This study found that the ARL15 gene affects adipocyte differentiation and adiponectin secretion, and suggests that ARL15 haploinsufficiency may predispose individuals to lipodystrophy.

In this study, abnormal glucose tolerance was found to be prevalent among young Indian women with PCOS, and the use of an oral glucose tolerance test significantly improved its detection.

This study found that C57BL/6 mice with a diet containing specific levels of vitamin A showed alterations in retinoid metabolism and increased frequency of cicatricial alopecias, suggesting dietary factors may play a role in this condition.

This study found that androgen signaling has complex effects on bone formation in male AR3.6-transgenic mice, with varying impacts based on the embryonic lineage of cells.

This review analyzes the potential mechanisms by which SARS-CoV-2 may exacerbate symptoms of benign prostatic hyperplasia and suggests a connection via ACE2 and androgen receptor pathways; it reports no new clinical results.

This study found that prenatal exposure to androgens caused long-lasting heart remodeling and left ventricular hypertrophy in female mice offspring, suggesting potential cardiac risks for daughters of mothers with PCOS.

This practical guide introduces methods to study human dermal white adipose tissue but does not report new clinical results, emphasizing available techniques and staining protocols.

This study found that early-onset baldness in African-American men is associated with an increased risk of developing prostate cancer and more aggressive tumors, with potential interactions involving age and smoking.

This article reviews the challenges in treating PCOS, noting the potential benefits of insulin sensitizers on ovulatory function and pregnancy outcomes, and calls for more long-term studies on metabolic interventions.

This study describes tumor necrosis factor inhibitor-associated psoriatic alopecia, highlighting the distinctive histologic feature of sebaceous lobule atrophy, which is potentially reversible and helps differentiate it from idiopathic psoriatic alopecia.

This review discusses the most popular non-surgical cosmetic procedures for men and highlights the importance of considering sex-specific factors for optimal treatment, but reports no new clinical results.

This study found that lipin 1β expression in both visceral and subcutaneous adipose tissue is significantly lower in PCOS patients compared to controls, suggesting its involvement in the pathogenesis of insulin resistance.

In this study, the researchers found that worse sleep scores were associated with progression of lower urinary tract symptoms and suggestively linked to their development in asymptomatic men.

This review discusses diagnostic criteria for polycystic ovary syndrome and highlights the challenges and risks of misdiagnosing women with other hyperandrogenism causes; it reports no clinical results.

This review discusses the onset of menstruation and related challenges in young women, with a focus on primary amenorrhea, its diagnosis, and management strategies, and reports no new clinical findings.

In this study, isotretinoin treatment in women with severe acne increased body weight and triglycerides but did not affect androgens or insulin sensitivity.

This review highlights the role of dermatologists in detecting early cutaneous signs of obesity-related metabolic syndrome, which may enable earlier treatment to prevent long-term consequences; it reports no new clinical results.

This study suggests that weight loss can improve fertility outcomes in overweight and obese women with PCOS, and letrozole should be considered the new first-line treatment over clomiphene citrate for anovulatory infertility in this population.

This study found that fasting insulin levels are associated with increased cardiovascular and metabolic risk factors in women with polycystic ovary syndrome.

This study found that manipulating AKR1D1 expression in human liver cells effectively regulates glucocorticoid clearance and receptor activation, highlighting its role in liver-specific steroid hormone regulation.