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Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.

MDP hydrogel heals wounds faster and better than other treatments in diabetic mice.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

New treatments for male hypogonadism are effective and should be personalized.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Light can turn on hair growth cells through a nerve path starting in the eyes.

Most hair follicle stem cells do not protect their DNA by dividing it unevenly.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Researchers developed a method to grow hair follicles using special beads that could help with hair loss treatment.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Stem cell niches are adaptable and key for tissue maintenance and repair.

Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.