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A 66-year-old woman's thick scalp and hair loss were confirmed as lipedematous alopecia, a rare condition possibly influenced by genetics, with no effective treatment known.

A patient with Ehlers-Danlos Syndrome improved after treatment for fat malabsorption and essential fatty acid deficiency.

Exosomes could improve skin and hair treatments but are limited by cost, production difficulty, and need for more research.

Not having the gene PLAAT3 leads to fat loss, high insulin resistance, and abnormal fat levels in the blood due to a disruption in fat cell development and function.

Pdgfα signaling helps maintain fat cells in the skin and is important for hair growth, wound healing, and fighting infections.

A woman with Parry-Romberg syndrome developed new curly hair on one side of her scalp, a condition not previously linked to the syndrome.

Aging changes hair stem cells and their environment, leading to gray hair and hair thinning, but understanding these changes could help develop treatments for hair regeneration.

Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.

Aging scalp skin contributes to hair aging and loss, and more research is needed to develop better hair loss treatments.

PDGF signaling is crucial for maintaining fat stem cells in the skin, and its level of activation can either preserve these cells or cause fibrosis.

Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.

A high fat lard diet may protect against skin fibrosis and affect hair growth.

Macrophages are more involved in Lichen planopilaris than in Frontal fibrosing alopecia.

Different types of stem cells in the skin contribute to the variety of melanoma forms.

Proper cell death regulation is crucial for normal hair follicle regeneration and skin remodeling.

Regenerative medicine shows promise for improving hair and skin but needs more research for standard use.

Special fiber materials boost the healing properties of certain stem cells.

Stem cells could improve plastic surgery but are not widely used due to cost and safety concerns.

Tiny vesicles from stem cells could be a new treatment for healing wounds.

New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.

The letter suggests that a modified fat processing technique may increase regenerative cells but calls for more trials to confirm its effectiveness for skin and hair treatments.

New regenerative medicine-based therapies for hair loss look promising but need more clinical validation.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.

The document concludes that the hCG protocol may help in obesity treatment and could be scientifically justified, but more research is needed.

Researchers created artificial human skin using special cells, which could help treat skin conditions like albinism and vitiligo.