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PCOS affects a similar percentage of Black and White women in the Southeastern United States.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

PCOS affects about 4% of women in the southeastern U.S. equally across Black and White populations.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Androgens can cause hair growth in some areas and hair loss on the scalp.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Targeting the skin's endocannabinoid system could help treat skin disorders.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Melatonin may help treat PCOS symptoms in rats.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

High levels of TNF-α may contribute to obesity and insulin resistance in PCOS, but not due to the C850T genetic variation.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

Chronic kidney disease can cause skin problems that affect patient quality of life, and treating these conditions can improve outcomes.

Adrenal gland disease is common in ferrets and causes hair loss and other symptoms.