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Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Blocking β-catenin in skin cells improves hair growth during wound healing.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

MDP hydrogel heals wounds faster and better than other treatments in diabetic mice.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

EVAL membranes help create cell structures that can regrow hair follicles.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Targeting the skin's endocannabinoid system could help treat skin disorders.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

The transscrotal testosterone patch normalizes hormone levels in men with AIDS and weight loss but does not improve weight, body mass, or quality of life.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Light can turn on hair growth cells through a nerve path starting in the eyes.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

The new micelle formulation delivers acne treatment more effectively and safely than current gels.

Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.