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Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.

Targeting TGFβ can improve skin immunity in older people.

DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.

PDGF signaling is crucial for maintaining fat stem cells in the skin, and its level of activation can either preserve these cells or cause fibrosis.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Skin wounds can create fat cells that help regenerate hair follicles, with BMP signaling playing a crucial role in this process.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.

Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.

The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.

N1-methylspermidine helps hair growth and reduces inflammation in hair follicles.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.

Lipedema is a painful fat disorder in women that's hard to treat, often worsens with hormonal changes, and requires symptom-focused therapies.

A high fat lard diet may protect against skin fibrosis and affect hair growth.

Developing microRNA-based treatments is hard but has potential.

p14ARF and p16Ink4a cause hair follicle stem cell aging and dysfunction.

Zinc/silicon-infused hydrogel helps regenerate hair follicles.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

ADSCs help in wound healing and skin regeneration but need more research for full understanding.

Targeting and modifying the stem cell niche can improve regenerative therapies.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Seaweeds have beneficial compounds for skin care, including anti-aging and protective effects.

Human dermal stem cells can become functional skin pigment cells.

Involucrin gene expression is controlled by specific proteins and signaling pathways.

Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Both estrogens and androgens are important for health in both males and females.

Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.