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PCOS is caused by both genetics and environmental factors like diet and obesity.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Different types of skin cells play specific roles in development, healing, and cancer.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Different types of stem cells and their environments are key to skin repair and maintenance.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Light can turn on hair growth cells through a nerve path starting in the eyes.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Lymphatic vessels are essential for hair follicle growth and skin regeneration.

Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.