7 citations
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November 2004 in “International Journal of Cosmetic Science” This review examines mechanical and chemical causes of hair fiber adhesion failure and fracture patterns in the cell membrane complex, but presents no new experimental results.
5 citations
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January 2012 in “Journal of Tissue Science & Engineering” In this study, collagen I decellularized scaffolds enhanced the growth and melanotic properties of hair follicle melanocytes, suggesting their potential as effective carriers for transplantation in vitiligo treatment.
4 citations
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March 2021 in “Journal of Surfactants and Detergents” This study found that hair treated with shampoo containing water-soluble silicone demonstrated smoother sliding and better detangling, compared to shampoo with water-insoluble silicone, due to differences in conditioning film formation.
December 2023 in “Biological & pharmaceutical bulletin” This study found that combining lecithin reverse wormlike micelles with isopropyl myristate enhanced the skin permeability of a model hydrophilic drug, facilitated by interactions with sebum in hair follicles.
This Ph.D. project aims to evaluate the self-assembling potential of hair keratin extracts and study the cellular response to both crude and purified keratins, highlighting their potential applications from biomedical to water remediation.
26 citations
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March 2018 in “Dermatology and Therapy” This study found that conditioned media from epidermal progenitor cells improved skin aging signs in a clinical trial and protected fibroblasts from oxidative stress in vitro.
8 citations
,
February 2014 in “Stem cells translational medicine” This study found that human mesenchymal stem cells overexpressing JAM-A improved hair follicle structure and hair formation in mice by reducing abnormalities such as curved and zigzagged follicles.
1 citations
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April 2021 in “Journal of Investigative Dermatology” This study found that Manganese PCA, Cinchona succirubra, and Leontopodium alpinum extracts may promote hair growth by enhancing VEGF secretion and activating the Wnt/b-catenin pathway in Human Hair Follicle Dermal Papilla Cells.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The researchers reported that disrupting the RPGRIP1L gene in mice impaired desmosome function, causing skin blistering, and their findings suggest that PKCβII inhibition could help treat pemphigus.
72 citations
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November 2012 in “PloS one” This study found that dysregulation of the folliculin-p0071 interaction may lead to changes in cell adhesion and signaling, contributing to conditions like emphysema and renal cell carcinoma.
34 citations
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October 2014 in “European journal of pharmaceutics and biopharmaceutics” This study found that adapalene-loaded solid lipid microparticles may enhance targeted drug delivery into sebum due to their similarity to sebum components, although both this formulation and a standard cream showed equivalent follicular penetration.
April 2023 in “Asia-pacific Journal of Convergent Research Interchange” This study found that treating bleached hair with a hair manicure improved several physical properties, such as tensile strength and elongation, compared to untreated hair, suggesting potential benefits for enhancing hair conditions cosmetically.
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that inducing miR-205 reduces actin contractility and stiffness in hair follicle stem cells and progenitors, stimulating hair regeneration in both young and old mice.
April 2016 in “Journal of Investigative Dermatology” This study found that adding cell adhesion-linked gene expression variables improved the identification of patients with SLN metastases within 90 days of melanoma diagnosis compared to using clinicopathologic variables alone.
April 2026 in “Microsystems & Nanoengineering” This study developed HA-gel-dex hydrogels with enhanced ECM-like properties and functionality, showing promise for 3D bioprinting, tissue repair, and as wound dressings due to improved cell interaction, cytocompatibility, antimicrobial synergy, and wound healing in mice compared to traditional ECM bio-inks.
This study found that Wnt7a protein expression increased after corneal epithelial injury and promoted human corneal epithelium cell proliferation by upregulating fibronectin and enhancing cell adhesion.
41 citations
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July 2020 in “Colloids and surfaces. B, Biointerfaces” This study suggests that adjusting the ratios of keratin-associated proteins to keratin intermediate filaments can create keratin/chitosan hydrogels with more consistent gel properties for tissue engineering.
3 citations
,
June 2019 in “Journal of cosmetic dermatology” In this study, tresses treated with pH 1.0 acid straightener showed better straightening but more damage to hair properties compared to those treated with pH 2.0.
August 2016 in “Journal of Investigative Dermatology” This study found that dihydrotestosterone alters the balance of Wnt pathway regulators in dermal papilla cells, hindering hair follicle stem cell differentiation and contributing to hair follicle miniaturization.
4 citations
,
December 2020 in “International journal of research - granthaalayah” This study found that tetracycline can adhere to hair follicle structures and disrupt cell metabolism, potentially damaging healthy human cells as well as pathogens.
125 citations
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May 2019 in “Phytomedicine” This review discusses the historical development, mechanisms of action, and potential new clinical applications of the drug cepharanthine, highlighting its multi-faceted pharmacological properties; it reports no new clinical results.
4 citations
,
January 2025 in “Journal of Materials Chemistry B” In this study, researchers developed a multifunctional, injectable hydrogel that adapts to irregularly shaped wounds, enhances healing, and shows potential antibacterial activity without significant toxicity, suggesting promise for treating chronic wounds.
May 2026 in “Scientific Reports” This study found that a bioactive borosilicate glass containing Sr and Cu ions exhibited promising mechanical strength, biocompatibility, and antibacterial activity, particularly the CuSr-1 wt.% composition, suggesting potential for use in orthopedic implants and bone tissue engineering.
July 2026 in “Frontiers in Bioengineering and Biotechnology” This study reports that Echinacea-loaded silk fibroin/chitosan dressings may effectively promote scarless skin regeneration and accelerate wound healing compared to conventional treatments.
41 citations
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May 2018 in “Nutrition and healthy aging” This study suggests that age-related changes in skin elasticity reduce its stability against wrinkling, and anti-aging strategies should focus on addressing elastic mismatches between skin layers.
8 citations
,
January 2021 in “Smart materials in medicine” This study found that a newly constructed composite hydrogel dressing, made from silk fibroin, chitosan, and halloysite, promoted hair follicle neogenesis, angiogenesis tissue regeneration, and scar reduction.
4 citations
,
October 2017 in “Advances in tissue engineering & regenerative medicine” In this study, a bioengineered construct using a biodegradable polycaprolactone mat cocultured with human keratinocyte and rabbit dermal fibroblast cells demonstrated potential as a tissue-engineered skin substitute, showing good cell adhesion and growth.
162 citations
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July 2011 in “Biomacromolecules” This study found that chitosan nanofibrillar scaffolds accelerated skin wound healing in mice by enhancing cell adhesion, proliferation, and regeneration of epidermis and dermis compared to other forms.
83 citations
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May 2022 in “Journal of Advanced Research” This study suggests that enhancing glycolysis in MSCs may improve their immune functions and therapeutic potential, although more evidence is needed to understand the direct metabolic mechanisms involved.
52 citations
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August 1978 in “Journal of Applied Polymer Science” Human hair's ability to get wet is complex and can change with treatments, damage, and environment.