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Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Oxidative stress contributes to hair graying and loss as we age.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Researchers found that hair shedding happens mostly when new hair is growing and involves a unique process.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.