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A boy with a rare skin condition and kidney disease improved with cyclosporine after steroids failed, suggesting a new treatment approach.

Different skin diseases show unique patterns of skin cell separation, cell death, and granular layer changes.

The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.

A rare genetic disease causes sparse hair and early blindness due to a gene mutation.

Meibomian glands are highly specialized and differ significantly from other sebaceous glands in structure and function.

The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.

The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.

Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.

Wool follicles are complex, involving interactions between different cell types and structures.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.

The boy's severe skin disorder is caused by two new mutations in his TGM1 gene.

The document concludes that Hidradenitis suppurativa is often underdiagnosed, lacks definitive treatment, and requires better awareness and management strategies.

Mycophenolate mofetil helped reduce steroid use in treating a dog's autoimmune skin disease.

Dermoscopy is useful for diagnosing and monitoring discoid lupus erythematosus by showing specific skin patterns.

Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.

Early diagnosis and treatment of discoid lupus erythematosus improve outcomes.

Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.

Dogs with generalized discoid lupus erythematosus have similar symptoms to humans and need continuous treatment.

The document concludes that diagnosing and managing plaque psoriasis, particularly in sensitive areas, is challenging and requires careful differentiation from similar skin conditions.

A cat had a rare skin disorder with hair loss and scaling, linked to a suspected tumor.

Surgical therapies for vitiligo vary in effectiveness, with combination therapy and medical tattooing recommended for better results.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Facial feminization surgery is effective in helping transgender women appear more feminine and has high patient satisfaction.

IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

Burn reconstruction improves with new techniques, materials, and tissue engineering.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.