research Guidelines for the Diagnosis and Treatment of Male-Pattern and Female-Pattern Hair Loss, 2017 Version
Use finasteride, dutasteride, and minoxidil for hair loss treatment.
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450-480 / 1000+ results research OR2AT4, an Ectopic Olfactory Receptor, Suppresses Oxidative Stress-Induced Senescence in Human Keratinocytes
OR2AT4 helps reduce aging and cell damage in human skin cells.
research Tribuloside Acts on the PDE/cAMP/PKA Pathway to Enhance Melanogenesis, Melanocyte Dendricity and Melanosome Transport
Tribuloside can increase skin pigmentation by enhancing melanin production and distribution.
research Proteome Analysis of Alpine Merino Sheep Skin Reveals New Insights into the Mechanisms Involved in Regulating Wool Fiber Diameter
Key proteins and pathways regulate wool fiber diameter in Alpine Merino sheep.
research Female Pattern Hair Loss and Its Therapy
New treatments are improving options for female hair loss.
research STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction, Hair Follicle Regeneration, and Wound Healing
Activating STAT5 in the skin's dermal papilla is key for starting hair growth, regenerating hair follicles, and healing wounds.
research Enzymes
The document provided an overview of various enzymes and their roles in biological and biochemical processes. It discussed the metabolism and inactivation of adenosine, the conversion of ATP to cAMP by adenylyl cyclase, and the regulatory functions of amino acid hydroxylases, cyclooxygenase enzymes, and decarboxylases, with implications for health conditions like immunodeficiency and cancer. It also highlighted the potential role of α-difluoromethylornithine in controlling hair growth and cancer treatment. Additionally, it covered the generation and inactivation of endocannabinoids, the role of inositol monophosphatase in mood disorders, and the functions of lipoxygenases, nitric oxide synthases, and phospholipase D in various physiological and pathological contexts.
research Topical Metformin as a Novel Therapy for Alopecia Areata Due to Its Immunologic Effects
Metformin, usually used for diabetes, can also help treat hair loss from alopecia areata due to its ability to reduce inflammation and stimulate new hair growth.
research The Role of ATP-Dependent Chromatin Remodeling in the Control of Epidermal Differentiation and Skin Stem Cell Activity
ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.
research Methotrexate in Dermatology
Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.
research Reversing Wrinkled Skin and Hair Loss in Mice by Restoring Mitochondrial Function
Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
research Hair Regrowth in Two Patients with Recalcitrant Central Centrifugal Cicatricial Alopecia After Use of Topical Metformin
Topical metformin helped regrow hair in two women with a hard-to-treat scarring hair loss condition.
research Melanocytes and Vitiligo and Hair Graying
Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.
research Notes From The Editor Emeritus, 2011–2013
Caffeine can stimulate hair growth, but the best dose and frequency for hair loss treatment are still unknown.
research Phosphodiesterase (PDE) Inhibitors for the Treatment of Inflammatory Skin Conditions
PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
research Transplantation Immunology: Solid Organ and Bone Marrow
Transplant success has improved with better immunosuppressive drugs and donor matching.
research Molecular Regulation of Melanocyte Senescence
The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.
research Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN
The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
research Skin Steroidogenesis in Health and Disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
research Effect of Leaves of Ginkgo Biloba on Hair Regrowth in C3H Strain Mice
Ginkgo biloba leaf extract may help hair regrowth and improve heart health.
research Understanding the Role of Prostaglandin E2 in Regulating Human Platelet Activity in Health and Disease
Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.
research Purification and Characterization of Rat Liver Minoxidil Sulphotransferase
Enzyme purified and characterized for minoxidil sulphation in rat liver.
research Minoxidil Induction of VEGF Is Mediated by Inhibition of HIF-Prolyl Hydroxylase
Minoxidil boosts hair growth by increasing blood flow and nutrients to hair follicles.
research Effect of Minoxidil on Pre- and Postconfluent Keratinocytes
Minoxidil prolongs cell life, slows aging, and may produce longer hairs.
research The Effect of Cilostazol, a Phosphodiesterase 3 (PDE3) Inhibitor, on Human Hair Growth with Dual Promoting Mechanisms
Cilostazol helps hair grow by making hair root cells grow faster and changing growth factor levels.
research Age-Related Hair Pigment Loss
Graying hair happens due to aging and might be delayed by new treatments.
research Novel Anti-Melanogenesis Properties of Polydeoxyribonucleotide, a Popular Wound Healing Booster
Polydeoxyribonucleotide (PDRN) may help lighten skin and treat hyperpigmentation.
research Novel Effect of Sildenafil on Hair Growth
Sildenafil, often used for erectile dysfunction, may help hair growth.
research Use of Metformin in Pediatric Age
Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.
research A Comparative Study of a New Food Supplement, Viviscal, with Fish Extract for the Treatment of Hereditary Androgenic Alopecia in Young Males
ViviScal®, a food supplement, was found to be highly effective in treating hereditary hair loss in young males, while fish extract showed no impact.