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Minoxidil, originally a blood pressure medication, is effective in treating hair loss in men and women, with different strengths recommended for each.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Applying a specific inhibitor lightens skin and hair color.

Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Melanocytes are important for skin and hair color and protect the skin from UV damage.

Understanding skin structure and development helps diagnose and treat skin disorders.

Scientists discovered a new way UVB light increases skin pigmentation through the ATP-P2X7 pathway.

Touching hair can activate nearby nerve cells through signals from the hair's outer layer.

Mitochondrial reactive oxygen species are essential for skin and hair development.

The skin's microbiome helps hair regrow by boosting certain cell signals and metabolism.

Hair follicle stem cells can help treat ulcerative colitis in mice by releasing beneficial exosomes.

PRP injections can increase hair density in people with androgenic alopecia.

Minoxidil increases cell layer permeability by reducing tight junction proteins and raising ROS levels.

TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.

Fermented papaya and mangosteen in hair care products helped prevent hair loss and improve hair thickness.

Adenosine helps hair grow longer and stronger by boosting certain growth factors and signaling pathways.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Biotin treatment can significantly improve hair loss and motor functions in certain metabolic disorders.

The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.

Keratinocytes control how melanocytes work.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.