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Diagnosing PCOS in teenagers should focus on signs of excess male hormones and not rely solely on ovarian ultrasound or irregular periods, and should be reassessed in adulthood.

Certain gene variations are not a major cause of male infertility in Nigerian men.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

Mutations in certain receptors can cause diseases and offer new treatment options.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Many skin patients also have mental health issues, and doctors should treat both together.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Crataegus pinnatifida extract may help increase hair growth and thickness in mice.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.

Microneedle technology is beneficial for drug delivery and could make vaccinations cheaper and more accessible.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

Taking too many vitamin and mineral supplements can cause serious health problems.

Inner city teens had high retention rates for the contraceptive implant, especially those with a history of abortion.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

The document suggests a new model for evaluating public research that better captures the full value of knowledge creation and use, using PCOS research as an example.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Skin lymphatic vessels are essential for hair growth.

The meeting focused on understanding, diagnosing, and finding treatments for irreversible hair loss diseases.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.

Gemcitabine and paclitaxel are effective and safe as first-line treatment for metastatic breast cancer.

Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.

Women with hyperandrogenic amenorrhea have similar bone density to healthy women but lower than androgenized women without amenorrhea, and high DHEAS levels might affect bone density.

Minoxidil in breast milk may harm nursing infants.

Managing PCOS is hard because it varies a lot, treatments are limited, and there's a lot of false information online.