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Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The document likely offers guidance on treating a woman's excessive hair growth, considering her symptoms and obesity.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Hair loss affects women's mental health more than men's, causing anxiety, low self-esteem, and social insecurity.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Preoperative pain assessment, regional anesthesia, and vitamin C can help prevent CRPS after surgery.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.