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Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.

Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

Certain cancer drugs interact with skin bacteria to cause acne-like rashes.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

The Notch signaling pathway is important for hair follicle development and could help create treatments for hair disorders.

MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.

Sex hormones' effects on COVID-19 are unclear and more research is needed to understand their potential as treatment.

Natural skincare products may help reduce sun damage and support the skin's daily cycle.

Nanocarriers can improve the effectiveness of herbal medicines in treating colorectal cancer.

COVID-19 may harm male reproductive health and lower testosterone levels, potentially affecting fertility and causing erectile dysfunction. More research is needed.

Men with higher androgen levels may have severe COVID-19 symptoms, but those on antiandrogen therapy are less likely to contract the virus and have milder symptoms. Anti-androgen drugs could potentially treat COVID-19, but more research is needed.

Statins may help treat alopecia areata by reducing harmful immune interactions.

COVID-19 can cause skin symptoms that might help spot the virus early, and treatments for it can also affect the skin.