research The Disintegrin/Metalloproteinase Adam10 Is Essential for Epidermal Integrity and Notch-Mediated Signaling
Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
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30 / 1000+ results research RBPJ Mutations Identified in Two Families Affected by Adams-Oliver Syndrome
Mutations in the RBPJ gene cause Adams-Oliver Syndrome.
research Adam10 Haploinsufficiency Causes Freckle-Like Macules in Hairless Mice
A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
research Hair-Cycle Dependent Differential Expression of ADAM 10 and ADAM 12
ADAM 10 and ADAM 12 proteins are involved in different stages of hair growth and could be targets for treating hair disorders.
research Analysis Of The Function Of ADAM17 In IRhom2 Curly-Bare And Tylosis With Esophageal Cancer Mutant Mice
Mutations in iRhom2 affect hair and skin in mice and are linked to esophageal cancer, with ADAM17 playing a crucial role.
research The Role of ADAM17 in PCOS Pathogenesis: A Review Paper
ADAM17 could be a potential target for treating PCOS.
research ADAM17 Variant Causes Hair Loss via Ubiquitin Ligase TRIM47 Mediated Degradation
A variant in the ADAM17 gene causes hair loss by increasing protein degradation through TRIM47.
research Adams–Oliver Syndrome: New Evidence in Variable Expressivity
The clinical signs of Adams-Oliver syndrome can vary greatly, even among family members.
research An Overview of Chemotherapy Side Effects on Patients with Prostate Cancer, Bladder Cancer, and Testicular Cancer at Haji Adam Malik General Hospital Medan from 2020-2022
Chemotherapy for prostate, bladder, and testicular cancer patients commonly causes hair loss, fatigue, and decreased appetite.
research The Articulations of Adam's Rib with the Lower Urinary Tract
The patient had complex urinary tract issues and ambiguous genitalia, with physical features suggesting a hormonal imbalance.
research The Association of Urolithiasis and Androgenetic Alopecia
Kidney stones and hair loss are significantly related in people under 60 years old.
research Andropause: A Misnomer for a True Clinical Entity
Men over 50 may experience hormone decline causing various symptoms, and proper management is crucial.
research Mechanisms of Disease: Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 as a Novel Treatment for Metabolic Syndrome
Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.
research Pleiotropic Role of Notch Signaling in Human Skin Diseases
Notch signaling disruptions can cause various skin diseases.
research Therapeutic Effect of Mesenchymal Stem Cells on Histopathological, Immunohistochemical, and Molecular Analysis in Second-Degree Burn Model
Bone marrow-derived stem cells improved healing and reduced scarring in second-degree burns in rats.
research A New Tool for Conditional Gene Manipulation in a Subset of Keratin-Expressing Epithelia
The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.
research Targeting Pathogenic MICA-NKG2D Interactions by Statins: A Novel Adjunct Treatment Strategy for Alopecia Areata Management?
Statins may help treat alopecia areata by reducing harmful immune interactions.
research Is Spironolactone Better Than Finasteride for Symptoms of Hirsutism in Transgender Women?
Spironolactone and finasteride are equally effective for hirsutism in transgender women.
research 2-Substituted 4-(Thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
research Book Review
The book provides a detailed guide on managing Polycystic Ovary Syndrome and is useful for physicians.
research The Prevalence of Skin Disease in the Geriatric Age Group
Older adults in Ottawa commonly have skin conditions like sun damage, dry skin, and hair loss.
research Chapter 28. Vitamin D: Production, Metabolism, Mechanism of Action, and Clinical Requirements
Vitamin D is important for regulating calcium, phosphate, and hair health.
research Plant Responses to Shade
Plants change their growth in response to shade based on light signals detected by phytochrome.
research Concurrence of Giant Cell Arteritis in a Patient with De Quervain's Thyroiditis
Spironolactone may help reduce hair loss in androgenic alopecia.
research Hair Loss: It's Not Just a Cosmetic Concern
Hair loss can cause significant emotional and psychological distress.
research Book Reviews
The document suggests "Occupational Skin Disease" is a useful standard text, finds "The Clinical Management of Itching" poorly organized, recommends "Atlas of Contact Dermatitis" for its illustrations, and values "Handbook of Diseases of the Hair and Scalp" for its information despite flaws.
research Inhibition of SARS-CoV-2 Entry Through the ACE2/TMPRSS2 Pathway: A Promising Approach for Uncovering Early COVID-19 Drug Therapies
Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.
research Serum Testosterone Levels and Clinical Signs of Hypogonadism in Men with Type 2 Diabetes
Men with type 2 diabetes often have low testosterone and signs of hypogonadism, especially if they are overweight.
research Facial Feminization Surgery: Current State of the Art
Facial feminization surgery is effective in helping transgender women appear more feminine and has high patient satisfaction.
research Gender Surgery Beyond Chest and Genitals: Current Insurance Landscape
Most insurance companies do not cover extra gender-affirming surgeries, with coverage being low and inconsistent.