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Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

Mice healed without scars as fetuses but developed scars as adults, suggesting scarless healing might be replicated with further research.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.

Alopecia areata has a complex genetic basis that was not fully understood as of 2001.

Proper skin toxicity management in chemotherapy is key to continuing treatment and keeping patient quality of life high.

Minoxidil effectively treats severe hypertension but has notable side effects.

Hair restoration surgery has improved with better techniques for natural looks and managing patient expectations, but it remains labor-intensive and requires careful consideration of potential complications.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

A woman had a skin reaction from a cough suppressant, dextromethorphan, which is a new cause of fixed-drug eruption.

Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.

Diagnose and manage hair issues in women by checking medical conditions and using personalized treatments.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.

New treatments and management strategies for skin conditions like melanoma and Spitz naevi were discussed at the dermatologists' meeting.

Anorexia Nervosa and Bulimia Nervosa are complex eating disorders with increasing incidence among young females, significant morbidity, and varying mortality rates, requiring more research for better treatment.

Combining proper shaving, topical treatments, and laser therapy effectively reduces Pseudofolliculitis Barbae.

Surgical hair restoration has improved since 1959, with new techniques like minigrafts, micrografts, and scalp reductions creating more natural hairlines and reducing bald skin, despite some risks and potential for scarring.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.