92 citations,
September 2015 in “Journal of Lipid Research” Skin fat helps with body temperature control and has other active roles in health.
20 citations,
June 2020 in “Stem Cell Research & Therapy” Using stem cells from fat tissue can significantly improve wound healing in dogs.
Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.
April 2019 in “Journal of Investigative Dermatology” Eating grape powder may reduce the severity of skin allergy symptoms.
10 citations,
December 2011 in “Cell Transplantation” Researchers successfully grew human hair follicle cells that could potentially lead to new hair loss treatments.
April 2021 in “Journal of Investigative Dermatology” Bacteria can help skin regenerate through a process called IL-1β signaling.
November 2018 in “Atlas of genetics and cytogenetics in oncology and haematology” WNT10B is linked to cancer development and affects survival and disease progression in various cancers.
54 citations,
November 2015 in “Methods in enzymology on CD-ROM/Methods in enzymology” Keratins are important for skin cell health and their problems can cause diseases.
11 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.
1 citations,
November 2018 in “Elsevier eBooks” The document concludes that transplantology has evolved with improved techniques and materials, making transplants more successful and expanding the types of transplants possible.
248 citations,
November 2011 in “The EMBO Journal” Wnt1/βcatenin signaling is crucial for heart repair after injury.
1 citations,
October 2017 in “Circulation” A new technology showed that the SOX9 gene might control heart scar formation after injury, suggesting new treatment possibilities.
129 citations,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
23 citations,
May 2013 in “Virology” HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
January 2012 in “Elsevier eBooks” New treatments for skin and hair repair show promise, but further improvements are needed.
238 citations,
April 2012 in “Cell stem cell” Targeting and modifying the stem cell niche can improve regenerative therapies.
91 citations,
July 2010 in “Tissue Engineering Part A” Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.
71 citations,
September 2006 in “Cell Transplantation” Fetal skin cells from a cell bank heal wounds faster and with less scarring than adult cells.
316 citations,
June 2017 in “Stem Cell Research & Therapy” Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.
188 citations,
March 2018 in “Frontiers in Immunology” Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.
70 citations,
February 2021 in “International Journal of Molecular Sciences” Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.
40 citations,
January 2009 in “Skin Pharmacology and Physiology” Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.
37 citations,
June 2021 in “Journal of the European Academy of Dermatology and Venereology” Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.
18 citations,
September 2020 in “International Journal of Nanomedicine” Both human and animal-derived small extracellular vesicles speed up skin healing equally well.
14 citations,
January 2021 in “Scientific Reports” Using micro skin tissue columns improves skin wound healing and reduces scarring.
14 citations,
April 2011 in “Cell Proliferation” Scientists can grow human hair follicle stem cells in a lab without changing their nature, which could help treat hair loss.
12 citations,
March 2011 in “Journal of pathology” Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.
1 citations,
April 2021 in “Journal of Investigative Dermatology” Activating TRPA1 reduces scarring and promotes tissue regeneration.
119 citations,
March 2020 in “Frontiers in Bioengineering and Biotechnology” Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
94 citations,
June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.