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Inhibition of 5α-Reductase Impairs Cognitive Performance, Alters Dendritic Morphology, and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice

research Inhibition of 5α-Reductase Impairs Cognitive Performance, Alters Dendritic Morphology, and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice

13 citations, January 2020 in “Neuroscience”

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

research Stem Cell Competition for Niche Occupancy: Emerging Themes and Mechanisms

13 citations, February 2010 in “Stem Cell Reviews and Reports”

Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.

research Cutaneous Lupus Concerns from the Patient Perspective: A Qualitative Study

8 citations, August 2021 in “Lupus Science & Medicine”

Patients with cutaneous lupus are most concerned about self-consciousness, physical symptoms, and disease progression.

research Alopecia Areata: Hyperactivity of the Hypothalamic–Pituitary–Adrenal Axis Is a Myth?

5 citations, May 2017 in “Journal of the European Academy of Dermatology and Venereology”

The study found no significant difference in stress hormone levels between people with alopecia areata and healthy individuals, suggesting that the disease is not caused by an overactive stress response system.

research Hair Loss

5 citations, October 1984 in “The BMJ”

Up to 50% of scalp hair can be lost before it appears thin, and treatment is only needed for hair loss caused by diseases or deficiencies.

research Treatment Options for Alopecia Areata

4 citations, September 2011 in “Expert Review of Dermatology”

Various treatments exist for alopecia areata, but none are completely satisfactory; choice depends on age, disease extent, and preference.

Immunohistochemical, Pharmacovigilance, and Omics Analyses Reveal the Involvement of ATP-Sensitive K+ Channel Subunits in Cancers: Role in Drug-Disease Interactions

research Immunohistochemical, Pharmacovigilance, and Omics Analyses Reveal the Involvement of ATP-Sensitive K+ Channel Subunits in Cancers: Role in Drug-Disease Interactions

3 citations, April 2023 in “Frontiers in Pharmacology”

ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.

Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women

research Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women

3 citations, May 2018 in “Reproductive Sciences”

The drug BAY 1158061 is safe, well-tolerated, and shows potential for treating diseases related to prolactin.

research Caraway, Chinese Chives, and Cassia as Functional Foods Considering Nutrients and Health Benefits

2 citations, March 2021 in “Carpathian Journal of Food Science and Technology”

Caraway, Chinese chives, and cassia may improve health and prevent diseases due to their nutrients and medicinal properties.

research Abstracts

2 citations, January 2019 in “Medizinische Genetik”

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

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