5 citations
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May 2020 in “Journal of the American Academy of Dermatology” This article proposes naming the visual identification of androgenic alopecia in COVID-19 patients as the "Gabrin sign" to indicate higher risk for severe symptoms, but reports no new clinical results.
March 2026 in “Materials Today Chemistry” Smart microneedles improve hair loss treatment by delivering drugs precisely with fewer side effects.
January 2026 in “Preprints.org” This review highlights recent advancements in nanotechnology-based approaches for treating androgenetic alopecia, focusing on enhancing drug delivery to hair follicles, controlled release, and follicular microenvironment modulation, while addressing safety, manufacturing, and regulatory challenges for clinical application.
In this study, personalized PRP therapy significantly increased hair density and diameter in a patient with androgenetic alopecia, highlighting its potential benefit but emphasizing the need for broader clinical trials.
December 2024 in “JEADV Clinical Practice” This study found that male patients with androgenetic alopecia were associated with an increased risk of varicose veins, but not other major vascular diseases.
January 2007 in “동물실험대체법학회지” This article reviews in vitro methods for evaluating whitening, anti-wrinkle, and hair growth ingredients in cosmetics, noting that more human-relevant evaluation methods with reliable biomarkers are needed; it presents no new clinical outcomes.
66 citations
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January 2010 in “Journal of The American Academy of Dermatology” This study reported that mycophenolate mofetil was effective in reducing signs and symptoms of active lichen planopilaris in 83% of patients who had failed multiple prior treatments.
5 citations
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May 2024 in “Journal of Cosmetic Dermatology” In this study, treatment with cell-derived nanovesicles from hair follicle mesenchymal stem cells improved photoaging signs in UVB-exposed mice and human dermal fibroblasts by reducing oxidative stress, enhancing cell proliferation, and promoting extracellular matrix production.
2 citations
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January 2006 in “Technical report” This chapter reviews the development of skin-specific outcome instruments for autoimmune diseases like cutaneous lupus erythematosus and dermatomyositis, highlighting a need for a broader community-involved process across other diseases but reports no new results.
1 citations
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January 2024 in “Dermatologic Therapy” This study found that both methotrexate and azathioprine were equally effective and well-tolerated in improving symptoms of lichen planopilaris over six months, with no significant difference between the two treatments in terms of efficacy.
1 citations
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January 2015 This study found that bursts of ERK activation in the skin, termed SPREADs, are linked to increased cell division and help synchronize cell cycle progression in living mice.
In this study, incorporating cetirizine into transferosome formulations significantly enhanced hair growth in mice and boosted IGF-1 and VEGF levels, suggesting that this method could be a promising alternative to traditional hair growth treatments, though further studies are needed to confirm its safety and suitability.
March 2026 in “Journal of the American Academy of Dermatology” In this study, patients with active lymphocytic cicatricial alopecia showed significant improvement using a three-stage treatment regimen involving Tofacitinib, Apremilast, and Crisaborole, with 93.5% experiencing marked improvement and only three mild adverse events reported.
January 2026 in “Cutaneous and Ocular Toxicology” This study found that Yangxuebushen Decoction significantly promoted hair regrowth and improved hair follicle structure in a cyclophosphamide-induced alopecia mouse model by reducing inflammation, oxidative stress, and apoptosis.
October 2025 in “Journal of Nanobiotechnology” This study reports that using a hydrogel-based therapy that dynamically regulates reactive oxygen species helps achieve skin regeneration in infected wounds, promoting organized dermal architecture with improved hair follicle and blood vessel formation, rather than scar formation.
In this open uncontrolled study on microneedling as an adjuvant therapy for frontal fibrosing alopecia, researchers observed stable frontotemporal recession measurements while patients reported improvements in quality of life and a reduction in inflammatory activity parameters.
This review discusses the role of the Wnt/β-catenin pathway in hair follicle development and how natural products that activate this signaling could be used to treat hair loss, but it reports no new experimental results.
2 citations
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July 2025 in “Advances in Therapy” In this study, patients with more severe self-reported hair loss and emotional or social limitations experienced lower quality of life and greater work productivity impairment, with even moderate hair loss causing significant well-being and daily activity impacts.
4 citations
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October 2024 in “American Journal of Clinical Dermatology” This study found that ritlecitinib improved patient-reported outcomes related to hair growth in individuals with alopecia areata, with some experiencing clinically meaningful hair regrowth, although changes in emotional symptoms and activity limitations were minimal and similar across treatment groups.
January 2026 in “International Journal of Dermatology” In this study, researchers reported that treating alopecia areata patients with ritlecitinib led to progressive improvements in emotional symptoms and activity limitations over 48 weeks, though the post hoc analysis and trial setting suggest caution in interpreting the findings for broader populations.
August 2021 in “Journal of the American Academy of Dermatology” In this study, both physician and patient reports revealed that more severe alopecia areata was associated with higher emotional symptoms and greater activity limitations among patients.
This study demonstrated that Reverse Protein Engineering can decrease the size of Firefly Luciferase from 550 to less than 80 amino acids, but further research is needed to ensure these smaller peptides retain bioluminescent activity.
April 2026 in “Lithuanian University of Health Sciences” In this study, cinnamic acid in solution form showed strong antifungal activity against Microsporum canis, but when incorporated into hydrogels, the acid's diffusion and resulting antifungal performance decreased, though it maintained effectiveness for potential prolonged exposure.
58 citations
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July 2018 in “Journal of Allergy and Clinical Immunology” Alopecia areata severity is linked to increased TH1 and TH2 activity.
29 citations
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February 2022 in “Frontiers in Cell and Developmental Biology” This review discusses strategies to improve CRISPR/Cas systems by addressing limitations like off-target effects and delivery inefficiencies, offering practical guidance and highlighting future applications, but reports no new research findings.
5 citations
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February 2011 in “Expert Opinion on Drug Discovery” This review discusses techniques and models for assessing hair growth activity but reports no new clinical findings, emphasizing the need for standardization and improved animal models.
3 citations
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June 2021 in “Frontiers in genetics” This study found that STAT3 directly inhibited the activity of the sheep FST gene promoter, consequently reducing cell proliferation and promoting a better understanding of hair follicle development mechanisms.
December 2023 in “International journal of molecular sciences” This in vitro study found sex chromosome differences affect steroidogenic enzyme activity and androgen receptor expression in human skeletal muscle cells, showing varied responses to testosterone exposure between 46XY and 46XX cells.
17 citations
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May 1998 in “Steroids” This study constructed a model to predict finasteride's inhibitory activity on 5α-reductase type 2 and calculated that a 1 μM plasma concentration, after 50 mg administration, matches prostate inhibition levels.
January 2026 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” This study developed a deep-learning model that accurately diagnosed alopecia areata with an accuracy of 88.92% and distinguished its activity levels with an accuracy of 83.33%, highlighting the potential for artificial intelligence in improving the diagnosis and treatment of this autoimmune hair loss condition.