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Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Oxidative stress contributes to hair graying and loss as we age.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Drug advertising has greatly increased, changing consumer behavior and raising concerns about its influence on healthcare and patient protection.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Lowering testosterone speeds up wound healing in male mice.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

BMP2 and BMP7 have opposite roles in feather formation.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.