In this study, researchers analyzed the chemical constituents of male and female Gynostemma longipes plants and different parts like roots and leaves, identifying significant variations in metabolites which could aid in assessing and selecting quality medicinal materials.
November 2018 in “Springer eBooks” Finasteride and minoxidil are effective, low-risk treatments for male hair loss, and patient education on these therapies is important.
November 2017 in “Asian journal of pharmaceutical and clinical research” This study predicted that 6-hydroxy genistein, coreximine, and scoulerine from Dadap leaves may act as anti-alopecia agents by interacting with JAK2, but further in-vivo testing is needed.
July 2017 in “International journal of Ayurvedic and herbal medicine” This study revealed that Madayantika siddha taila, containing sesame oil, showed effectiveness in treating Darunaka (seborrhea capitis) by addressing aggravated Vata and Kapha doshas.
June 2001 in “Annals of Internal Medicine” This commentary discusses challenges in maintaining proper blinding in placebo-controlled trials, illustrated by a study where zinc and placebo lozenges were nearly indistinguishable in taste by participants.
November 1983 in “American Biology Teacher” This article revisits the genetics of pattern baldness but reports no new clinical findings.
January 2020 in “Química Nova” This study used Density Functional Theory-based computational methods to analyze finasteride's molecular properties, finding that the GGA/PW91 method closely matches experimental data for vibrational frequencies and geometric parameters.
49 citations
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April 2012 in “Phytotherapy Research” This study found that topical Rosmarinus officinalis leaf extract improved hair regrowth in mice and inhibited androgen-associated mechanisms involved in hair loss.
138 citations
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August 1985 in “Journal of The American Academy of Dermatology” Minoxidil promotes hair growth in male pattern baldness.
68 citations
,
April 2002 in “Journal of Alternative and Complementary Medicine” This study suggests that botanical 5AR inhibitors like Serenoa repens and β-sitosterol may improve symptoms of androgenetic alopecia, with 60% of treated subjects showing improvement compared to placebo.
45 citations
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December 2018 in “Lasers in Medical Science” In a 24-week randomized trial, this study found that the RAMACAP laser helmet significantly increased hair density and diameter in androgenetic alopecia patients compared to a sham device, although limitations included a small sample size and potential issues with the control used.
45 citations
,
February 2005 in “Steroids” This study reported that certain newly synthesized steroidal derivatives showed stronger inhibitory activity against the 5α-reductase enzyme than finasteride in hamsters, suggesting their potential as enzyme inhibitors.
42 citations
,
July 2015 in “Cosmetics” This review discusses the use of cosmetic nanocarriers to improve hair appearance and reports no new experimental results.
36 citations
,
December 2002 in “Experimental dermatology” This study found that procyanidin B-3, a compound isolated from barley extract, may promote hair growth by enhancing hair epithelial cell growth and counteracting TGF-β1's growth-inhibiting effects in vitro and in vivo.
31 citations
,
March 2013 in “Gene” This study sequenced and analyzed the goat skin transcriptome, revealing genes involved in signal transduction and cell communication that are differentially expressed during hair growth phases, providing insights for Cashmere goat breeding.
27 citations
,
May 2017 in “Marine Drugs” This study found that Undariopsis peterseniana extract may promote hair growth by activating specific cellular pathways, suggesting potential for treating alopecia.
11 citations
,
February 2004 in “Clinical and Experimental Ophthalmology” In this case report, the authors suggest an association between prolonged finasteride use and anterior subcapsular cataracts, as observed in a 43-year-old man, marking the first reported instance.
8 citations
,
July 2022 in “Frontiers in plant science” This review outlines the current understanding of how pH contributes to root hair development and reports no new experimental findings.
5 citations
,
May 2018 in “PloS one” This study demonstrated that both classical and atypical BSE strains from cattle can be transmitted to goats, highlighting the importance of surveillance in protecting public health.
4 citations
,
January 2014 in “The Scientific World Journal” This study found that deer antler aqueous extract may promote hair growth in mice by extending the anagen phase and increasing cell proliferation in the hair follicle region.
3 citations
,
August 2021 in “Uro” This review concludes that global literature supports the lipidosterolic extract of Serenoa repens as efficacious and safe for treating lower urinary tract symptoms, with some studies showing equivalence to common pharmacologic agents.
2 citations
,
October 2020 in “Journal of Pharmacology and Experimental Therapeutics” This study found that in a mouse model of bronchopulmonary dysplasia, minoxidil administered at 50 mg/kg/day did not impact lung development or inhibit lysyl hydroxylation.
2 citations
,
April 2016 in “Más dermatología” This study found that the dietary supplement RJ-SP4AGA significantly improved hair growth and reduced hair loss in post-menopausal women with androgenetic alopecia over 16 weeks.
1 citations
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January 2024 in “Food Science and Technology Research” In this study, researchers evaluated the hair growth-promoting effects of strawberry water-extract on human follicle dermal papilla cells and found it enhanced cell metabolism, though it did not significantly alter hair growth-related gene expression.
March 2026 in “Research Square” This study developed a novel regenerative platform using nanozyme-enabled materials combined with exosomes and laser stimulation to enhance wound healing in a mouse model, which more effectively regulated reactive oxygen species and improved early angiogenesis and collagen organization compared to conventional methods.
January 2024 in “Más dermatología” This study discusses how hair characteristics, such as color, thickness, and volume, change with age and hormonal factors, affecting perceived age, and introduces concepts of hair aging and the nuanced diagnosis between androgenic and senile alopecia.
December 2017 in “Elsevier eBooks” This study suggests that unliganded vitamin D receptors in mice may cause more severe skeletal and mineral ion defects than VDR-null conditions, and vitamin D analogues may restore function in specific VDR mutations.
27 citations
,
December 2005 in “Journal of Cosmetic Dermatology” This study found that topical application of niacin derivatives significantly increased hair fullness in women with female pattern hair loss compared to a placebo after six months.
23 citations
,
January 2002 in “Journal of Cutaneous Medicine and Surgery” This study suggests that finasteride may affect hair follicle growth by altering the expression of caspases and XIAP, potentially regulating the anagen phase of hair growth.
2 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This review discusses unique anatomical features and management strategies for crown alopecia but reports no new clinical findings, focusing instead on surgical techniques for natural-looking results and optimal density.