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TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.

DNA methylation changes are linked to hair growth cycles in goats.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.

Chitosan-based dressings reduce inflammation and speed up skin wound healing.

Two different mutations in the vitamin D receptor gene cause different symptoms and responses to treatment in Lebanese patients with hereditary rickets.

COVID-19 can cause hair loss, and treatments like PRP and stem cells might help.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

Blocking EGFR in skin cells doesn't majorly increase inflammation markers.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.