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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.

Freezing gamma-irradiated amniotic fluid may help hair growth and speed up the growth phase.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.

Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

Chitosan-based dressings reduce inflammation and speed up skin wound healing.

The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Changthangi goats have specific genes that help produce Pashmina wool.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

DNA methylation changes are linked to hair growth cycles in goats.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Platelet-rich treatments can help improve wound healing and tissue repair.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

A new mutation in the Hr gene causes hair loss in mice, similar to a human hair disorder.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Platelet-Rich Plasma (PRP) could potentially help regrow hair in people with Alopecia Areata, but more research is needed to confirm its effectiveness.

Women with PCOS face many health risks, but exercise, a healthy diet, and weight management can help.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.