28 citations
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November 2017 in “Molecular and cellular endocrinology” This review examines the roles of testosterone, dihydrotestosterone, and estradiol in activating male sexual behavior in laboratory animals and humans, reporting no new clinical results.
19 citations
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September 2020 in “Pharmaceutics” This study investigated a new formula called SV-loaded nanospanlastics for topical application to treat androgenic alopecia. It showed similar effectiveness to minoxidil lotion but with fewer adverse effects when used to enhance dermal delivery and efficacy of sodium valproate.
11 citations
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December 2024 in “Stem Cell Research & Therapy” In this study, hUCMSCs-Exo significantly accelerated wound healing in rat perianal fistulas with notable safety, potentially through the activation of the HIF-1α/TGF-β/Smad signaling pathway.
7 citations
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July 2024 in “Current Issues in Molecular Biology” This review examines the complex mechanisms that regulate skin stem cell development, activation, and differentiation, emphasizing the molecular signaling pathways that influence their fate and contribute to skin homeostasis.
4 citations
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August 2018 in “Facial Plastic Surgery Clinics of North America” This review discusses the use of platelet-rich plasma in treating androgenetic alopecia and alopecia areata, observing overall positive clinical responses without identifiable complications, and reports no new clinical results.
3 citations
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September 2021 in “Journal of Food Science and Nutrition” This study found that red ginseng extract may stimulate hair growth in a mouse model by enhancing dermal papilla cell proliferation and activating skin antioxidant defenses.
2 citations
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May 2023 in “Experimental dermatology” In this study, researchers used advanced four-dimensional optical imaging techniques to observe changes in skin afflicted with acne, finding increased epidermal thickness, keratinized hair follicles, inflammation, and aggregated blood flow, helping to distinguish between inflammation and reparative phases of acne progression.
April 2026 in “International Journal of Drug Delivery Technology” In this study, phytochemical analysis and molecular docking suggested that bioactive compounds in several Ayurvedic herbs may interact persistently with hair growth and antifungal protein targets, indicating potential as plant-based treatments for dandruff and hair loss.
March 2026 in “International Journal of Innovative Technologies in Social Science” This review summarizes current clinical evidence on platelet-rich plasma, highlighting its effectiveness in treating androgenetic alopecia and as an adjunctive therapy for acne scars, while noting challenges in standardizing preparation techniques.
This study found that fibroblasts from Emery-Dreifuss muscular dystrophy patients with certain genetic mutations overexpress markers of fibrosis, and gene correction techniques reduced fibrogenic molecule expression in cell models, suggesting potential therapeutic applications.
May 2025 in “Journal of medical and dental science research.” This article discusses the potential role and mechanisms of platelet-rich fibrin therapies in androgenetic alopecia management, exploring their possible benefits over existing treatments but reports no new clinical results.
May 2025 in “Journal of International Medical Research” In this study, micrografting technology was found to potentially shorten healing time compared to other grafting techniques, especially in treating burns, though results showed high heterogeneity and a risk of bias.
March 2025 in “World Journal of Stem Cells” This study found that human adipose-derived MSC exosomes (hADSC-Exos) may enhance dermal papillary cell proliferation and migration by activating the Wnt/β-catenin signaling pathway, potentially reversing the effects of dihydrotestosterone in androgenetic alopecia.
October 2024 in “Journal of Cosmetic Dermatology” This study found that downregulating miR-30a-5p levels inhibits apoptosis and promotes proliferation in hair follicle stem cells, which is associated with the activation of the Wnt/β-catenin signaling pathway.
In this narrative review, the authors explored various rehabilitative techniques, including injections and physical therapies, that may enhance aesthetics and psychosocial wellbeing in patients with disabilities, emphasizing a multidisciplinary approach to improve both functional and cosmetic outcomes.
This study examined the molecular communication in psoriasis cells, highlighting unique immune cell interactions and identifying new features of the hair follicle cell-psoriasis axis. It suggests the potential for targeted therapies at the single-cell level to improve psoriasis treatment.
February 2020 in “International Journal of Current Microbiology and Applied Sciences” This study found that canine hair follicle stem cells in vitro expressed markers associated with multipotency, suggesting their potential role in the hair cycle.
January 2019 in “Springer eBooks” PRP may help with hair loss and improve hair quality with few side effects, but more research is needed.
35 citations
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February 2015 in “Experimental Dermatology” This study found that human follicle dermal papilla cells promote survival, proliferation, and tubulogenesis of microvascular endothelial cells, highlighting their significant role in hair follicle vascular remodeling.
4 citations
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August 2020 in “Applied Materials Today” This study suggests that human dermal fibroblasts can be converted into dermal papilla cell-like cells using microencapsulation, which may facilitate hair follicle regeneration in mice without chemical or genetic reprogramming.
July 2025 in “Dermatologica Sinica” In this study, compound glycyrrhizin promoted hair regrowth in a testosterone-induced alopecia mouse model and increased human hair dermal papilla cell proliferation, likely through activating the Wnt/β-catenin pathway.
This study found that garlic exosomes induced hair growth in rats by increasing anagen follicle counts and activating multiple signaling pathways, including Wnt-1, β-catenin, and TGF-β1.
April 2019 in “Journal of Investigative Dermatology” In this pilot study, combined platelet-rich plasma therapies showed potential benefits for improving skin elasticity and vascular network density in morphea patients, but the small sample size limits definitive conclusions.
March 2022 in “Molecules” This study found that adenosine promotes hair growth by stimulating the Wnt/β-catenin pathway in cultured human dermal papilla cells through activation of the adenosine receptor.
188 citations
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January 2022 in “PubMed” This review discusses recent advancements in congenital adrenal hyperplasia research, including improved diagnostic techniques, alternative treatments, and insights from long-term outcome data, but it reports no new clinical results.
5 citations
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January 1993 in “PubMed” In this study, retinoic acid treatments induced glandular and feather formation in embryos by altering positional values and activating specific retinoic acid nuclear receptor gene expression.
July 2024 in “ADMET & DMPK” This review discusses the potential for surface-modified nanostructured lipid carriers to enhance hair regrowth by improving drug absorption and stability, focusing on their use with agents like minoxidil and finasteride for hair loss treatment.
215 citations
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November 2000 in “Journal of Investigative Dermatology” This study found that the tetracycline-regulated transcription system effectively controls conditional gene expression in the mouse epidermis, allowing suppression and activation of specific genes with doxycycline.
203 citations
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May 2022 in “Pharmaceutics” This review discusses ongoing concerns and advancements in the use of gelatin as a biomaterial in tissue engineering, highlighting improved tissue mimicry through techniques like 3D bioprinting and suggesting a future focus on disease detection and diagnosis rather than treatment.
124 citations
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November 2019 in “International Journal of Molecular Sciences” This review discusses different processing methods for isolating human AD-SVFs/AD-MSCs using various kits and reports no new clinical results, highlighting the need for standardized preparation techniques.