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Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Matriptase is highly active in hair follicles and sebaceous glands, especially during hair growth phases.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Certain natural compounds called terpenes may help prevent prostate cancer.

Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.

Finasteride causes temporary cell death in BPH tissues.

This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Certain drugs that block specific enzymes can help treat prostate diseases.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

Saw palmetto helps with nighttime urination and urine flow, similar to finasteride.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

New research on prostamide F2α has led to treatments for glaucoma and eyelash growth and may have more medical uses.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Finasteride effectively blocks enzyme causing male pattern baldness.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.

Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.