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Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.

Matriptase is highly active in hair follicles and sebaceous glands, especially during hair growth phases.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Certain natural compounds called terpenes may help prevent prostate cancer.

Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Overexpressing SSAT enzyme reduces prostate tumor growth in mice.

Ocimum basilicum L. and red Oryza sativa L. may help with hair loss and prostate issues.

Chlormadinone acetate is useful for birth control and treating various hormonal issues.

The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.

Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Men on 5-alpha-reductase inhibitors might have worse COVID-19 outcomes.

Finasteride effectively blocks enzyme causing male pattern baldness.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Quick, selective detection of tadalafil and finasteride in human plasma developed.

The traditional herbal formulas Yongdamsagan-Tang and Paljung-san, along with the drug finasteride, can reduce inflammation and may work together without affecting each other's effectiveness against benign prostatic hyperplasia.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Saw palmetto helps with nighttime urination and urine flow, similar to finasteride.

Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.