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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

Caspase-7 has functions in skin and hair that are not related to cell death.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Minoxidil treatment increases aorta elasticity and reduces stiffness in aged mice, potentially helping with age-related heart issues.

Finasteride affects brain stress and enzyme activity differently in various regions, possibly helping with liver-related brain issues.

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

A plant mixture extract helped grow hair by boosting cell growth and growth factors while blocking a hair loss-related enzyme.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

Ishige sinicola, a type of seaweed, may help hair grow by blocking a hair loss-related enzyme and boosting important cell growth.

A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Certain skin proteins can form anchoring structures without the protein AMACO.

The model shows that filament flexibility and amino acid differences affect how fast intermediate filament proteins assemble.

Minoxidil can reduce functions related to androgen receptors.

Women with Polycystic Ovary Syndrome (PCOS) have lower levels of a substance called DIAPH1 in their blood, which is linked to changes in sugar metabolism and insulin resistance.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Targeting TGFβ can improve skin immunity in older people.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Keratins are important for skin cell health and their problems can cause diseases.

Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.

Certain electric currents can promote hair growth by activating specific cell pathways.

A protein in plants needs to bind two lipids to help with root hair growth, and this process is similar across different plant species.

C-reactive protein helps monocytes stick to blood vessel cells by causing oxidative stress.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.