118 citations,
August 2010 in “Developmental Cell” MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” MicroRNA-205 helps hair grow by changing the stiffness and contraction of hair follicle cells.
6 citations,
January 2015 in “Biochemical Society Transactions” The Ysc84/SH3yl1 protein family is important for cell movement and the process of taking in materials by interacting with actin and cell membranes.
56 citations,
December 2011 in “The Plant Journal” AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
13 citations,
December 2012 in “Cells” Targeting the actin cytoskeleton could improve skin healing and reduce scarring.
4 citations,
January 2013 in “Advances in Experimental Medicine and Biology” Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
141 citations,
August 2017 in “Developmental Dynamics” The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
100 citations,
November 2017 in “EMBO Reports” Metabolic signals and cell shape influence how cells develop and change.
788 citations,
February 2007 in “Nature” The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
211 citations,
November 2018 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
32 citations,
January 2017 in “Orphanet journal of rare diseases” FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
11 citations,
April 2013 in “Journal of Proteomics” Found different proteins in balding and non-balding cells, giving insight into hair loss causes.
8 citations,
December 2017 in “Skin appendage disorders” WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.
7 citations,
April 2012 in “Biomolecular concepts” Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
1 citations,
September 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” The meeting highlighted major advances in skin research, including new findings on skin microbes, genetic links to skin diseases, and improved treatments for various conditions.
January 2024 in “Wiadomości Lekarskie” Robotic hair transplantation with AI offers more reliable, precise, and efficient hair restoration.
129 citations,
July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
3 citations,
June 2017 in “Methods” Researchers created a model to understand heart aging, highlighting the role of microRNAs and identifying key genes and pathways involved.
1 citations,
December 2016 Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.
3 citations,
February 2022 in “Frontiers in cell and developmental biology” A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.
February 2012 in “Clinical and Experimental Dermatology” Many adult women experience unexplained excessive hair shedding, often starting before age 40.
31 citations,
July 2017 in “Clinical Science” MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
39 citations,
April 2020 in “IntechOpen eBooks” Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
2 citations,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.
7 citations,
March 2020 in “PloS one” α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.
11 citations,
January 2012 in “Journal of cell science” Rac1 is essential for proper hair structure and color.
3 citations,
May 2022 in “Oncogene” Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
29 citations,
March 2019 in “British Journal of Dermatology” Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
172 citations,
March 2019 in “The EMBO Journal” FERONIA and LRX proteins help control cell growth in plants by regulating vacuole expansion.