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Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

Finasteride effectively reduces hair growth in women with polycystic ovary syndrome or idiopathic hirsutism.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.

Adrenal disorders can cause lasting brain and behavior issues in children.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Finasteride and flutamide both reduce hair growth, but finasteride has fewer side effects.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

Some medications might reverse gray hair, especially those that reduce inflammation or stimulate pigment production, and vitamin B might help.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Somatostatin may help protect hair follicles from immune attacks.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.