January 2024 in “ACS Biomaterials Science & Engineering” In this study, researchers developed a microfluidics-based method to generate hair follicle germs on a large scale for potential hair regeneration therapies, demonstrating efficient hair follicle regeneration following transplantation into mice.
December 2023 in “ACS Sustainable Chemistry & Engineering” Keratin can be successfully taken from human hair using a mix of choline chloride and ethanolamine.
November 2023 in “ACS Omega” This study reported that a novel cationic liposome formulation for delivering encapsulated Cas9 protein and sgRNA successfully decreased SRD5α2 mRNA expression by 29.7% in vitro, suggesting a potential alternative treatment option for conditions like prostate cancer and benign prostatic hyperplasia without current drug side effects.
November 2023 in “ACS Applied Polymer Materials” In this study, the researchers developed a new method using H2O2/TiO2/UV for extracting human hair keratins rapidly, yielding higher protein and enabling the production of keratin films with better hemostatic performance and varied wound-healing properties compared to films from traditionally extracted keratin.
November 2023 in “ACS Nano” In a mouse model of deep skin burns, this study found that a neuro-inspired biomimetic microreactor, when delivered through a hydrogel and activated by near-infrared light, significantly promoted functional skin regeneration, sensory recovery, and hair follicle formation.
August 2023 in “ACS applied materials & interfaces” In this study, researchers developed an innovative wound healing patch combining electrical and chemical components, which effectively guided recovery in animal scald models by promoting collagen deposition and the regeneration of skin structures.
May 2023 in “ACS Biomaterials Science & Engineering” This study found that a silk fibroin/sodium alginate scaffold effectively delivers human umbilical mesenchymal stem cells to promote scarless wound healing and hair follicle regeneration in vivo by inducing specific cellular processes and mitigating endoplasmic reticulum stress.
October 2022 in “ACS Applied Materials & Interfaces” This study reports that the newly developed SA-Ca(II) hydrogel has tunable mechanical properties, high biocompatibility, and potential applications in wearable protections and stimuli-responsive electronics.
October 2020 in “ACSMʼs Health & Fitness Journal” This overview describes various disorders, including haphephobia, alopecia areata, and urinary incontinence, summarizing potential treatments and management strategies specific to each condition.
April 2023 in “ACS Biomaterials Science & Engineering” This review highlights the importance of using 3D scaffolds in vitro to support hair follicle regeneration, emphasizing how these structures help maintain cell function and mimic the natural environment, which is crucial for developing hair follicle organoids for transplantation.
March 2023 in “ACS Applied Materials & Interfaces” This study reports that a water-soluble microneedle patch with minoxidil-loaded microspheres showed similar or better hair regeneration effects in mice with less frequent application compared to daily topical minoxidil.
71 citations
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September 2007 in “Cancer” This review discusses various prostate cancer prevention strategies and reports no new clinical results; the authors highlight the need for ongoing research in this area.
33 citations
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February 2021 in “Journal of Medicinal Chemistry” This study found that novel MPC inhibitor analogues with specific chemical modifications promoted significant hair growth in shaved mice when applied topically.
6 citations
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June 1983 in “Cancer” This study found that a chemotherapy regimen combining CMFVP and ACP treatments for unresectable metastatic breast cancer yielded a 66.7% overall response rate, with premenopausal women responding more favorably than postmenopausal women.
1 citations
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February 2023 in “Advancements in Homeopathic Research” This review highlights the limited evidence available for homeopathy in the treatment of alopecia areata, indicating the need for more rigorous studies.
1 citations
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April 2004 in “Cancer” This study describes that 65% of patients receiving imatinib mesylate in a patient assistance program experienced skin hypopigmentation, primarily in ethnically Chinese individuals, suggesting variability across populations.
May 2023 in “Animal Reproduction Update” This article reviews the use of hair cortisol concentration as a biomarker to assess long-term stress in both animals and humans, but it reports no new experimental results.
May 2026 in “International Research Journal of Ayurveda & Yoga” This review explores the Charaka samhita's concept of Ashtanindita purusha, identifying eight physical constitutions traditionally regarded as undesirable due to their association with various diseases, and aims to correlate these with contemporary genetic, endocrinological, and metabolic disorders.
December 2025 in “Advancements in Homeopathic Research” This article discusses the anatomical structure and physiological functions of the skin without reporting new research findings.
March 2024 in “Advancements in Homeopathic Research” This study reported that patients experiencing hair loss after Covid-19 infection, particularly women, showed significant improvement with homeopathic remedies, suggesting homoeopathy's potential role in addressing Covid-related, stress-induced hair loss where modern medicine lacks specific interventions.
May 2023 in “Advancements in Homeopathic Research” This study investigated the effectiveness of a botanical formulation, Zauberӧl®, on testosterone-induced alopecia in Wistar rats, focusing on ingredients such as Arnica montana and Hibiscus Rosa sinensis. Results are not reported in the abstract.
823 citations
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February 1998 in “Analytical Chemistry” Method detects finasteride in plasma at very low concentrations.
282 citations
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April 2007 in “Journal of Agricultural and Food Chemistry” This study found that apple polyphenol extract, particularly oligomeric procyanidins, inhibited pancreatic lipase activity and reduced triglyceride absorption in both mice and humans.
180 citations
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February 2023 in “Journal of Chemical Information and Modeling” In this paper, Chemistry42—a software integrating AI with computational and medicinal chemistry—demonstrated efficiency in designing novel molecular structures targeting DDR1 and CDK20, with properties validated in both in vitro and in vivo studies.
162 citations
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July 2011 in “Biomacromolecules” This study found that chitosan nanofibrillar scaffolds accelerated skin wound healing in mice by enhancing cell adhesion, proliferation, and regeneration of epidermis and dermis compared to other forms.
159 citations
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July 2014 in “Molecular pharmaceutics” This study found that MPEG-dihexPLA micelles significantly improved the skin deposition of tacrolimus compared to a marketed ointment, suggesting better targeted delivery with reduced systemic absorption.
148 citations
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April 2009 in “Molecular Pharmaceutics” This study reports that three synthesized PSMA-targeted radioimaging agents demonstrated high affinity and specific localization to prostate cancer tumors in a mouse model, highlighting their potential for cancer detection and monitoring.
136 citations
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March 1996 in “Journal of the American Chemical Society” This study explains finasteride's high potency and specificity as a mechanism-based inhibitor for treating benign prostatic hyperplasia by detailing its interaction with human type 2 steroid 5α-reductase.
125 citations
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February 1971 in “Biochemistry” Specific cross-linkages help make hair proteins stable and strong.
111 citations
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August 2002 in “Journal of Medicinal Chemistry” This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.