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Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Tofacitinib is effective and safe for severe hair loss, but full regrowth is less likely after 10 years of hair loss.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Fullerenes show potential in skin care but need more safety research.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Tofacitinib is somewhat effective for alopecia areata, but more research is needed on its safety and long-term effects.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.