50 citations,
November 2015 in “Journal of pharmacological sciences” α-mangostin nanoparticles improved acne with minimal irritation.
49 citations,
January 1994 in “The Journal of Steroid Biochemistry and Molecular Biology” RU 58841 may treat acne, hair loss, and excessive hair growth.
48 citations,
May 2012 in “Journal of cosmetic and laser therapy” Fractional bipolar RF energy safely and effectively treats acne scars.
46 citations,
August 2016 in “Journal of The American Academy of Dermatology” The study found that family history, personal history of adolescent acne, no pregnancies, hirsutism, office work, stress, and low intake of fruits/vegetables and fish are risk factors for adult female acne.
46 citations,
August 1990 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.
46 citations,
September 2016 in “Clinical, Cosmetic and Investigational Dermatology” Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.
43 citations,
January 2007 in “Gynecological Endocrinology” Finasteride improves acne and hair loss in women with normal testosterone.
43 citations,
May 1986 in “Clinics in Endocrinology and Metabolism” Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.
43 citations,
November 1975 in “Archives of Dermatology” Testosterone affects hair loss, acne, and excessive hair growth, and antiandrogens can help treat these conditions.
43 citations,
September 2012 in “International Journal of Dermatology” Hormonal therapies are safe and effective for treating adult women's acne.
42 citations,
May 2009 in “Contraception” The oral contraceptive with ethinyl estradiol and chlormadinone acetate is effective in treating moderate acne.
42 citations,
August 2016 in “Nanomedicine” The new adapalene formulation using TyroSpheres is more effective and less irritating for acne treatment.
42 citations,
December 2014 in “Clinical, cosmetic and investigational dermatology” Nonablative radiofrequency treatments, especially microneedle and fractional types, can improve acne scars by 25%–75% after 3-4 sessions, with full results in 3 months and some side effects.
41 citations,
June 2016 in “Reviews in endocrine and metabolic disorders” Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.
41 citations,
June 2010 in “Anais Brasileiros de Dermatologia” Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.
40 citations,
September 2012 in “European Journal of Dermatology” Laser hair removal significantly improves acne keloidalis nuchae, especially with early treatment.
40 citations,
May 2010 in “American Journal of Clinical Dermatology” AKN might be a skin marker for metabolic syndrome.
39 citations,
January 2018 in “British journal of dermatology/British journal of dermatology, Supplement” Acne and hidradenitis suppurativa have different causes and risk factors, but both are driven by inflammation and may benefit from treatments targeting interleukin-1.
39 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
39 citations,
May 2011 in “Human Immunology” Genetics play a role in acne, but how exactly they contribute is not fully understood.
39 citations,
January 1980 in “Dermatology” Cyproterone acetate was effective in treating acne, hirsutism, and alopecia with few side effects.
37 citations,
January 2013 in “Postepy Dermatologii I Alergologii” Isotretinoin effectively reduces acne but causes dry skin, higher skin pH, more redness, and hair loss.
37 citations,
September 2005 in “Australasian Journal of Dermatology” A man with scalp and neck skin issues improved after a year of oral isotretinoin.
35 citations,
March 2012 in “Journal of dermatological science” The document concludes that advanced methods show the presence of P. acnes in acne lesions but do not prove it causes acne.
33 citations,
April 2021 in “Journal of Dermatological Treatment” New ways to treat acne are being discovered.
32 citations,
October 2003 Spironolactone is better than placebo for reducing excessive hair growth in women, but its effectiveness for acne is unclear due to small study sizes.
31 citations,
June 2015 in “British Journal of Dermatology” Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.
31 citations,
December 2010 in “International Journal of Andrology” Men with testicular cancer were less likely to experience baldness and severe acne.
30 citations,
June 2015 in “British Journal of Dermatology” Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.
29 citations,
March 2019 in “British Journal of Dermatology” Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.