![Synthesis and Activity of 8-Substituted Benzo[c]quinolizin-3-ones as Dual Inhibitors of Human 5α-Reductases 1 and 2](/images/research/efc54340-66d6-4f27-9930-045ac023f903/small/15248.jpg)
research Synthesis and Activity of 8-Substituted Benzo[c]quinolizin-3-ones as Dual Inhibitors of Human 5α-Reductases 1 and 2
New compounds were made that effectively block enzymes related to prostate issues and hair loss.
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research Treatment of Androgen Excess in Females: Yesterday, Today, and Tomorrow
The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
research Combination of an Antiandrogen and a 5α-Reductase Inhibitor: A Further Step Towards Total Androgen Blockade?
Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.
research Effects of Isotretinoin on the Hair Cycle
Isotretinoin at a low dose for three months does not significantly affect hair growth.
research Photobiomodulation in Dermatology: Harnessing Light from Visible to Near Infrared
Low-intensity light therapy is effective for skin healing, reducing inflammation, and treating various skin conditions.
research Comparative Study of a Novel Tool for Follicular Unit Extraction for Individuals with Afro-Textured Hair
The curved nonrotary punch is better for hair extraction in people with tightly curled hair.
research Anticytokine Therapy, Particularly Anti-IFN-γ, in Th1-Mediated Autoimmune Diseases
Blocking interferon-gamma might help treat various autoimmune diseases.
research Evaluation of ChatGPT Dermatology Responses to Common Patient Queries
ChatGPT can be a helpful dermatology resource but should not replace professional consultations.
research A Systematic Review on the Lipid Composition of Human Hair
Lipids are crucial for healthy hair, protecting it from damage and breakage.
research Cardiovascular Disease-Associated Skin Conditions
Some skin conditions may increase the risk of heart disease, and understanding their connection could lead to better treatments.