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Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Fullerenes show potential in skin care but need more safety research.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.

Scientists created stem cells that can grow hair and skin.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Iranian veterans exposed to sulfur mustard suffer from long-term skin itching and eye damage, with some risk of skin cancer and ongoing management challenges.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Fatty acid transport protein 4 is essential for skin and hair development.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Skin fat helps with body temperature control and has other active roles in health.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.