This study found that tenuazonic acid from Alternaria alternata can cause significant damage to vital organs in mice at low doses and highlights the need for regulatory measures to manage its risk in agricultural products.
May 2018 in “Dermatologic Surgery” This journal overview highlights the expansive coverage of cosmetic and reconstructive skin surgery, but reports no new research findings.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a novel mechanism by which dsRNA-induced TLR3 activation and retinoic acid pathways contribute to new hair follicle formation after deep wounds in mice and suggested a similar potential in humans.
April 2018 in “Journal of Investigative Dermatology” The researchers reported that nicotinic acid normalized excessive sebaceous lipogenesis without affecting basal lipogenesis and suggested potential anti-acne benefits.
January 2018 in “Hair therapy & transplantation” This study aimed to identify possible associations between a hair pull test and various pathological, biochemical, and hematological parameters in Czech patients with different types of alopecia.
September 2016 in “Journal of the Society of Cosmetic Scientists of Korea” This study found that Resina Pini and its main component, abietic acid, significantly promoted hair growth in a mouse model of androgenic alopecia by inhibiting 5α-reductase activity.
April 2016 in “Journal of Investigative Dermatology” This study suggests that lithocholic acid may enhance hair regeneration in alopecia by activating vitamin D receptors in human dermal papilla cells.
January 2016 in “International journal of clinical pediatrics” In this study, ultrastructural examination of hair in children treated with valproic acid showed a normal hair surface and cuticular pattern, despite reported hair changes with the drug.
September 2014 in “Daehan miyong hakoeji” Adding 2% glycerin or hyaluronic acid to permanent wave treatments reduces hair damage, with hyaluronic acid being more effective.
June 2014 in “Zagazig Journal of Pharmaceutical Sciences/Zagazig Journal of Pharmaceutical Science” This study reports that using ascorbic acid or orlistat can significantly inhibit the metabolism of testosterone esters into malodorous metabolites by axillary bacteria, suggesting potential new deodorant applications.
March 2014 in “Journal of The American Academy of Dermatology” Mycophenolic acid may help hair grow by activating pathways important for hair growth.
June 2010 in “The Knowledge Bank (The Ohio State University)” This study found that inhibiting retinoic acid synthesis in mouse hair follicles allowed WNT signaling to remain active, suggesting potential implications for developing treatments for hair disorders and skin cancer.
February 2010 in “Journal of the American Academy of Dermatology” Lactic acid cream can help improve skin bumps known as eruptive vellus hair cysts.
January 2010 in “Laboratory animal science” This study found that Heterogeneous Victoria A Acid Capsules significantly reduced sebaceous acid capsule diameter and hair follicle size in a rabbit model of micro-acne.
September 2009 in “European journal of paediatric neurology” Biotin supplements did not significantly reduce hair loss in rats on valproic acid.
July 2009 in “International Journal of Cosmetic Science” This study found that 53% of Japanese women have straight hair while 47% have varying degrees of curved hair, with distinct structural differences observed in the internal makeup of curved hair fibers.
This article discusses the roles of retinoic acid in cellular differentiation and its side effects like hair loss, but reports no new clinical findings.
February 2009 in “Journal of the American Academy of Dermatology” Both skin products were equally effective in improving facial discoloration and skin quality.
This study found that in mice, the combination of azelaic acid and vitamin B6 enhanced hair regrowth, follicle elongation, and thickness more than individual treatments.
This article reviews different generations of synthetic retinoids for dermatological use, discussing their efficacy and significant side effects, but reports no new clinical results.
January 2005 in “Medical Entomology and Zoology” The reinforced collagen sponge helps grow normal hair in mice.
January 2004 in “Linchuang pifuke zazhi” In this study, all-trans retinoic acid was found to promote differentiation and inhibit proliferation of amelanotic melanocytes from human hair follicles, suggesting a potential role in melanogenesis.
This study found that RXR and RAR proteins were detectable in normal human skin, suggesting they may play a role in epidermal cell differentiation and hair and gland physiology.
January 1992 in “Biology of the Cell” Retinoic acid receptors are important for hair follicle development.
January 1989 in “Skin research” In this study, an oleanolic acid-containing scalp treatment increased terminal hair counts significantly more than placebo in men under 50 with androgenic alopecia, but only three showed clinical improvement, with minimal side effects reported.
January 2023 in “Pharmaceutics” In this study, researchers developed a new topical atraric acid formulation, AA-TF#15, which showed a significantly higher drug penetration and increased hair regrowth in mice compared to minoxidil and finasteride treatments, suggesting its potential effectiveness for treating scalp androgenic alopecia.
August 2022 in “Metabolic Brain Disease” In this study with a mouse model of catamenial epilepsy, ferulic acid may effectively reduce seizure susceptibility and depression-like behavior by influencing hormone levels and neurotransmitter activity.
October 2020 in “Journal of Pharmaceutical Sciences” This study found that using gallate-containing formulations like EGCG or tannic acid increased the solubility and controlled release of finasteride in microspheres, enhancing its dermal penetration in pig skin by 10 to 50 times compared to a control.
August 2020 in “Benha Journal of Applied Sciences” This study observed that patients with androgenetic alopecia had significantly higher serum FABP4 levels compared to healthy controls, suggesting FABP4 may be involved in the condition's pathogenesis.