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July 2012 in “EFSA Journal” The Panel concluded that there is no established cause and effect relationship between the specified vitamin and pumpkin seed oil combination and the maintenance of normal hair in healthy adults.
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January 2012 In this study, the researchers cloned and analyzed the CRABP I gene in Inner Mongolian cashmere goats, finding its highest mRNA expression at 90 days in embryo skin compared to later stages.
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September 2007 in “Neuromuscular disorders” This study suggests that long-term treatment with valproate, acetylcarnitine, folic acid, and vitamin B12 may benefit children with SMA types II and III by improving muscle strength and function without significant adverse effects.
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January 2000 in “PubMed” The treatment slightly increased hair growth and was safe for most women.
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January 1996 in “European Journal of Dermatology” This study found that VEGF activated and minoxidil differentially modulated arachidonic acid metabolite production in hair dermal papilla cells, enhancing PGE2 and LTB4 but reducing PG6KF1α.
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November 1988 in “Veterinary Record” In this case study, oral folic acid therapy resulted in noticeable improvement and eventual recovery from hair loss and skin issues in a three-week-old Charolais calf.
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September 1986 in “Journal of the Forensic Science Society” This study found that hair root sheaths can be accurately typed for erythrocyte acid phosphatase, adenylate kinase, and adenosine deaminase, consistent with blood typing results from the same donors.
September 2026 in “Portuguese Journal of Dermatology and Venereology” In this review, the researchers discuss the potential effectiveness of azelaic acid peels for treating acne vulgaris, melasma, and other skin conditions, while acknowledging that the precise role of these peels in dermatology is not yet fully established due to limited studies.
August 2026 in “Nature Communications” This study found that early mitochondrial reprogramming, specifically through fatty acid oxidation fueling oxidative phosphorylation, is crucial for initiating differentiation in epidermal stem cells, highlighting a potential therapeutic target for differentiation defects in skin disorders.
August 2026 in “Pharmaceutics” In this study, researchers developed a dexpanthenol-infused nanotechnological platform within hyaluronic acid hydrogels that promoted wound healing in mice by providing a protective barrier and significantly enhancing skin regeneration, including increased fibroblast activity and tissue remodeling.
August 2026 in “Materials Technology” This study developed a multifunctional TA-MoS2-SF hydrogel for diabetic ulcer treatment, demonstrating enhanced photothermal bactericidal effects, immune environment remodeling, and fibroblast proliferation, suggesting it may serve as an effective 'antibacterial-immunomodulatory-repair' strategy.
July 2026 in “International Journal of Pharmaceutics X” In this study, researchers developed a biopolymer-based dual-layer wound dressing that significantly improved healing outcomes in a 14-day rat model, reporting 94% wound closure by day 15 and enhanced tissue regeneration, swelling properties, and cell viability.
July 2026 in “Journal of Pharmacy and Pharmacology” In this study, gelatin methacrylate hydrogel dressings co-loaded with resveratrol, 18-β-glycyrrhetinic acid, and berberine showed enhanced capabilities in wound closure, infection clearance, and skin structure regeneration in mice with infected wounds compared to dressings with single agents.
June 2026 in “Frontiers in Physiology” In this study, a topical cream containing 3% lactic acid ferment lysate (VHProbi ® MixP) was found to significantly reduce sebum, porphyrin levels, and pore size, while increasing hydration and improving skin texture in participants with oily skin over a 60-day period.
This study found that periodic red light exposure in aged mice increased histone acetylation and activated metabolic processes in keratinocytes, mitigating cellular aging through enhanced fatty acid oxidation and altered gene expression related to lipid metabolism.
This study found that periodic red light exposure increased histone acetylation and activated metabolic processes in aged mice, leading to enhanced fatty acid oxidation and the mitigation of cellular aging by influencing gene expression and metabolic regulation.
May 2026 in “Phytomedicine” May 2026 in “Fibers and Polymers”
May 2026 in “Frontiers in Medicine” In this study, a keratolytic shampoo with 2% salicylic acid was found to effectively reduce scab severity in male patients after hair transplantation without causing adverse symptoms, leading to high patient satisfaction and no recorded adverse events.
April 2026 in “Phytotherapy Research” This study found that glycyrrhizic acid may reduce the cutaneous toxicity caused by Osimertinib in mice, suggesting its potential as an adjunct treatment in clinical settings.
March 2026 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” In this study, patients with resistant alopecia areata treated with 35% trichloroacetic acid showed significantly better outcomes compared to those receiving superficial cryotherapy, with TCA demonstrating "excellent" results in 37.5% of cases versus 6.25% for cryotherapy.
March 2026 in “Inflammopharmacology” This study found that ursolic acid at 50 mg/kg improved biochemical, hormonal, and ovarian histopathological markers in a rat model of PCOS, suggesting its potential as a therapeutic option.
March 2026 in “Frontiers in Veterinary Science” This study found that all-trans retinoic acid (ATRA) inhibits proliferation and promotes apoptosis in secondary hair follicle-derived dermal papilla cells from cashmere goats, likely via the TGF-β2/Smad2/3 signaling pathway.
In this study, topical latanoprost acid applied daily for 6 months increased hair count and improved trichoscopic markers among women with hair loss, suggesting its potential for treating female androgenetic alopecia, particularly at a 0.05% concentration.
In this study, a novel CT@GA-gel hybrid hydrogel was developed for diabetic wound treatment, demonstrating improved mechanical properties, tissue adhesion, and chronic wound healing benefits, including immune regulation and re-epithelialization, due to enhanced crosslinking and ROS scavenging by incorporated carbon dots.
January 2026 in “Journal of Dermatological Science” This research observed that Salvianolic acid B (Sal B) significantly promoted hair regeneration in vivo and in vitro, outperforming minoxidil in a mouse model of androgenetic alopecia, by activating Wnt/β-catenin and mTORC2/Akt pathways and upregulating MMPs and MAPKs.
January 2026 in “Open Science Framework” This scoping review aims to map current knowledge about treatment strategies for alopecia caused by VPA (valproic acid) across various patient groups, identifying reported management strategies, supporting evidence, observed outcomes, and areas needing further research, but results are not provided.
January 2026 in “In Silico Research in Biomedicine” This study used computational methods to explore the potential of betulinic acid from Ziziphus spina-christi in treating alopecia, suggesting its possible protective effects on hair follicles by enhancing genomic stability and reducing oxidative damage, meriting further experimental validation.
December 2025 in “Journal of Drug Delivery Science and Technology” In mouse studies, this research found that combining ginsenoside Rg3 and glycyrrhizic acid with minoxidil improved treatment outcomes for androgen alopecia by addressing both symptoms and root causes, notably activating the Wnt/β-catenin pathway and promoting hair follicle cell proliferation.
December 2025 in “Journal of the European Academy of Dermatology and Venereology” This source states that an image was mistakenly misused in the supplementary materials but clarifies that this does not impact the study's main findings. The authors have corrected the error for accuracy and transparency.