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Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Androgens, like testosterone, are crucial for early testicular descent in rats.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Microneedling is promising for treating various skin issues but needs more research to confirm its effectiveness and safety.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Iranian veterans exposed to sulfur mustard suffer from long-term skin itching and eye damage, with some risk of skin cancer and ongoing management challenges.

Male pattern baldness involves smaller hair follicles, larger oil glands, and other tissue changes, but not major blood supply issues.

Oxidative stress affects hair loss in men with androgenetic alopecia.

The genus Sophora has compounds with potential health benefits and could lead to new drugs, but more research is needed to understand their effects and safety.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Treatments for melanin disorders exist, but more effective options needed.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.