July 2026 in “Dermatology Practical & Conceptual” This study found that while both microneedling-assisted methotrexate and triamcinolone acetonide treatments led to improvements in recalcitrant alopecia areata, methotrexate-treated areas had significantly better outcomes in terms of SALT score reduction, patient satisfaction, and relapse rates, suggesting its superior short-term efficacy.
This study found that radiofrequency microneedling significantly enhanced the absorption of topical triamcinolone acetonide, with insertion depth being more influential than RF energy levels.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a new triamcinolone acetonide serum combined with a microneedling device, showing promise for treating alopecia areata by targeting hair follicles in a less invasive, patient-friendly way with confirmed drug solubility, compatibility, and safety.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a low-viscosity triamcinolone acetonide serum, used with a derma stamp microneedling device, to improve targeted treatment of alopecia areata, reporting favorable drug solubility, spreadability, and permeation to hair follicles, while maintaining skin safety.
April 2026 in “Indian Journal of Dermatology” This study concluded that platelet-rich plasma therapy was as effective as intralesional triamcinolone acetonide in treating localized alopecia areata on the scalp.
February 2026 in “Journal of Cosmetic Dermatology” In this study, researchers found that combining cryotherapy with triamcinolone injections is equally effective as triamcinolone alone for treating patchy alopecia areata on the scalp and face, with no significant difference in outcomes between the two methods.
January 2026 in “Dermatology Practical & Conceptual” In a systematic review and meta-analysis, the researchers found that intralesional triamcinolone acetonide was more effective than cryotherapy for achieving significant hair regrowth in patients with patchy alopecia areata, although both treatments had distinct safety profiles.
January 2026 in “International Journal of Medical and All Body Health Research” This study found that both intralesional corticosteroids (TAC) and platelet-rich plasma (PRP) are effective for treating patchy alopecia areata, with TAC providing faster early results but PRP offering better long-term safety and lower relapse rates.
November 2025 in “Archives of Dermatological Research” Using a higher concentration of triamcinolone acetonide leads to faster hair regrowth in scalp patchy alopecia areata.
October 2025 in “Indian Dermatology Online Journal” In this study, researchers found that a 2.5 mg/mL concentration of triamcinolone acetonide was more effective than a 1.25 mg/mL concentration for promoting hair regrowth in patients with limited patchy alopecia areata, with significant differences in regrowth observed after six months.
September 2025 in “Tạp chí Da liễu học Việt Nam” This study found that both 2.5 mg/mL and 5 mg/mL concentrations of intralesional triamcinolone acetonide are effective for treating patchy alopecia areata, but the higher concentration promoted greater hair regrowth and density with more side effects.
September 2025 in “The health sciences AUS.” This review discusses the efficacy and safety of intralesional triamcinolone acetonide for treating acne keloidalis nuchae, highlighting its significant effectiveness with rare side effects when used properly.
August 2025 in “Saudi Pharmaceutical Journal” This study developed a new suspended ointment formulation containing neomycin sulfate and triamcinolone acetonide, which showed promise for treating neurodermatitis and chronic eczema by ensuring stable composition, effective skin penetration, and no skin irritation.
July 2025 in “The Egyptian Journal of Hospital Medicine” This study found that intralesional methotrexate and triamcinolone acetonide have similar efficacy for localized alopecia areata in adults, but differ in safety profiles, with methotrexate associated with hyperpigmentation and triamcinolone with atrophy.
July 2025 in “International Journal of Trichology” This study found that intralesional methotrexate and triamcinolone acetonide were significantly more effective than Vitamin D3 for hair regrowth in patients with alopecia areata.
July 2025 in “Journal of the Pakistan Medical Association” In this study, intralesional triamcinolone acetonide combined with 5-fluorouracil was more effective for treating keloids, showing a good to excellent response in 95% of cases and fewer side effects, compared to triamcinolone acetonide alone, which achieved a 70% response rate.
June 2025 in “Indus journal of bioscience research.” This study conducted at the Pakistan Emirates Military Hospital found that microneedling combined with topical triamcinolone acetonide was significantly more effective and well-tolerated than microneedling alone for treating localized alopecia areata, with 60% of participants achieving complete recovery compared to 5% in the microneedling-only group.
May 2025 in “Journal of the Egyptian Womenʼs Dermatologic Society” This randomized controlled trial found that intralesional vitamin D3 was as effective and safe as intralesional triamcinolone acetonide for treating patchy alopecia areata on the scalp, with no significant influence from serum vitamin D levels on treatment response.
January 2025 in “Journal of Cutaneous Medicine and Surgery” In this clinical trial, adding topical calcipotriol to intralesional triamcinolone acetonide significantly increased hair regrowth efficacy in scalp alopecia areata patches compared to steroids alone, but not in beard patches, with a lower incidence of atrophy observed.
November 2024 in “Journal of the European Academy of Dermatology and Venereology” In this pilot study, cryotherapy using a device that precisely controls cooling duration improved hair regrowth for patchy alopecia areata when applied for 20 seconds with two freeze-thaw cycles, similar to standard triamcinolone acetonide injections, but not when applied for 10 seconds.
July 2024 in “JAAD Case Reports” This study reports two cases of central serous chorioretinopathy developing after intralesional corticosteroid injections to the scalp for alopecia areata, suggesting a potential association that warrants cautious use and monitoring for ocular complications.
April 2024 in “Skin research and technology” This study retrospectively observed that combining microneedle minoxidil with triamcinolone acetonide showed clinical efficacy in treating alopecia areata, a condition marked by sudden patchy hair loss.
November 2023 in “PubMed” This study showed that intralesional injections of pentoxifylline may be an effective and safe alternative to triamcinolone acetonide for treating localized alopecia areata.
October 2023 in “Benha Journal of Applied Sciences” The authors of this meta-analysis suggest that intralesional injections of methotrexate and vitamin D3 may serve as safe and effective alternatives to triamcinolone acetonide for treating localized alopecia areata in adults, with trichoscopy aiding early detection of treatment effects.
October 2023 in “Indian journal of ophthalmology. Case reports” This case report described acute vision loss in a patient after forehead injections of triamcinolone acetonide for alopecia areata, attributing retinal artery occlusion to embolization by steroid particles.
July 2023 in “Research Square (Research Square)” In this case report, Triamcinolone Acetonide injections effectively improved mouth opening in patients with Oral Submucous Fibrosis, but both developed symptoms of Cushing's Syndrome, prompting the need for careful monitoring due to potential adverse effects when using this treatment.
July 2023 in “Deleted Journal” In this case report from Cipto Mangunkusumo Hospital Jakarta, alopecia areata was identified as the most common type of baldness in the facility's skin and genital polyclinics from 2009 to 2011, representing 39.7% of cases.
July 2023 in “Journal of Pakistan Association of Dermatologists” PRP injections are more effective than triamcinolone for treating alopecia areata.
February 2023 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” In this study, both intralesional and microneedling treatments with triamcinolone acetonide significantly reduced alopecia areata markers, but their clinical responses did not differ significantly, suggesting microneedling as a safe, cost-effective option with minimal complications.
This study observed that both intralesional triamcinolone acetonide and microneedling with triamcinolone acetonide significantly reduced alopecia areata severity, with no significant difference in effectiveness between the two treatments, suggesting microneedling as an effective and less invasive option.