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PGD2 stops hair growth and is higher in bald men with AGA.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Some medicinal plants can help heal wounds and may lead to new treatments.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Low iron levels may be linked to some types of hair loss in women.

Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Laser device increases hair density, safe for treating hair loss in men and women.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Silver nanoparticles coated with substances like PEG showed strong antibacterial effects and improved wound healing when used in hydrogels.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.