13 citations,
May 2011 in “Bioorganic & Medicinal Chemistry” Changing the 6-position on benzopyran molecules affects insulin release, with some compounds showing strong inhibitory effects.
20 citations,
September 2005 in “Endocrinology” Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.
24 citations,
October 2019 in “Biomaterials Research” Minoxidil in HA-PLGA nanoparticles effectively treats alopecia through skin delivery.
12 citations,
June 2001 in “Bioorganic & Medicinal Chemistry” Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.
6 citations,
April 2014 in “European journal of medicinal chemistry” New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.
129 citations,
January 2004 in “Journal of medicinal chemistry” Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.
30 citations,
December 2018 in “International Journal of Biological Macromolecules” Chitosan and surface-deacetylated chitin nanofibers may help treat hair loss.
19 citations,
July 2018 in “Medicines” Juniperus plants contain compounds with potential for developing various medical treatments.
2 citations,
January 2019 in “Biomecánica” Hyaluronic acid and versican are important for skin healing and hair growth and might help in regenerative medicine.
3 citations,
March 2022 in “Polymers” Substances from Ascidian tunics might help treat hair loss as effectively as Minoxidil.
July 2023 in “International Journal of Cosmetic Science” Biopolymers are increasingly used in cosmetics for their non-toxicity and skin benefits, with future biotech advancements likely to expand their applications.
9 citations,
March 2022 in “Antioxidants” Synthetic antioxidants are effective, cheap, and stable, with some like zinc and cholecalciferol reducing child and cancer deaths, but the safety of additives like BHA, BHT, TBHQ, and PEG needs more research.
1 citations,
December 2019 Selenium is essential for health, but too much or too little can cause problems; blood selenium levels are a good measure of intake.
February 2023 in “Frontiers in Bioengineering and Biotechnology” Optical imaging and light therapy show promise for diagnosing and treating liver injury caused by surgery.
2 citations,
October 2023 in “Biology” Cobalt is important for health but too much or too little can cause health problems, and its environmental buildup is a concern.
38 citations,
November 2005 in “Epilepsia” Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.
14 citations,
June 2021 in “Expert Opinion on Therapeutic Patents” New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.
12 citations,
May 2017 in “Medicine” Oral isotretinoin was recommended for a 21-year-old woman with severe acne.
3 citations,
January 2003 in “Synthetic Communications” Scientists made two new chemicals that might help treat diseases caused by male hormones.
47 citations,
November 2012 in “Expert Opinion on Therapeutic Patents” The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
33 citations,
January 2015 in “Journal of Cosmetic Dermatology” Familial frontal fibrosing alopecia affects premenopausal women too, and early diagnosis is important, but no proven medication exists yet.
14 citations,
October 2020 in “Journal of ethnopharmacology” Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.
8 citations,
October 2014 in “Journal of analytical toxicology.” Chemical hair straightening significantly reduces detectable drug levels in hair.
3 citations,
September 1989 in “Journal of Investigative Dermatology” Methyl caprate greatly increases drug absorption through the skin and is better than other enhancers.
December 2011 in “Drug Research” The document shows the state of pharmaceutical patents as of 1999, focusing on treatments for various diseases.
287 citations,
January 2013 in “Journal of Ginseng Research” The ginseng market has potential for growth and needs new products and better marketing.
182 citations,
November 2017 in “Molecular Aspects of Medicine” The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
166 citations,
November 1990 in “Journal of Investigative Dermatology” Minoxidil sulfate stimulates hair growth.
125 citations,
January 1999 in “Drugs” Finasteride effectively treats baldness but may cause sexual side effects.
123 citations,
December 2015 in “Journal of Neuroendocrinology” New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.