February 2016 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A hair test can accurately predict if a person with hair loss will respond to minoxidil treatment.
December 2025 in “Zagazig University Medical Journal” This review discusses polydioxanone threads as a promising, minimally invasive treatment for androgenetic alopecia in both males and females, but notes that further research is needed to optimize protocols and outcomes.
September 2025 in “AESTHETIC OROFACIAL SCIENCE” This study found that polidioxanona threads increased hair density and satisfaction in treating various types of alopecia, with no adverse events reported, though the small sample limits broader conclusions.
January 2021 in “Hair therapy & transplantation” This study reports encouraging results in treating androgenetic alopecia by combining injectable PRF and PDO thread insertion on the scalp.
February 2026 in “Journal of Korea Society of Ingrielogy” This review discusses the potential immuno-regenerative effects of polydioxanone threads in hair loss treatment, focusing on tissue responses and immune modulation, but does not report clinical results.
January 2017 in “Journal of cosmetology & trichology” In this study, polydioxanone threads significantly reduced hair loss and promoted hair regrowth in patients with androgenetic alopecia who did not respond to minoxidil and finasteride.
January 2023 in “Al-Azhar International Medical Journal (Print)” This pilot study found that using polydioxanone monofilament threads for scalp stringing resulted in significant hair regrowth and increased hair density in male patients with vertex androgenetic alopecia (crown baldness) over six months, showing favorable and promising outcomes.
3 citations
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January 2025 in “PubMed” This study compared the effectiveness of different thread types in improving collagen profiles in UVB-exposed aging model rats, finding that PCL threads were more effective than PDO and PLLA in enhancing dermal collagen characteristics.
1 citations
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January 2024 in “Egyptian Dental Journal /Egyptian Dental Journal” This study observed that injecting minimally cross-linked hyaluronic acid with PDO smooth threads in female patients with dry, cracked lips led to significant improvements in lip texture, elasticity, and reduced fissure depth, effects that lasted up to nine months with additional booster injections.
January 2025 in “SSRN Electronic Journal”
July 2025 in “Egyptian Journal of Medical Research” This study found that platelet-rich plasma significantly improved hair density and thickness compared to monofilament thread implantation in treating androgenetic alopecia.
October 2025 in “Advanced Healthcare Materials” In a study on wound healing, researchers described injectable POEGMA‐DA hydrogels as a promising non-toxic alternative to traditional wound closure methods, showing effective tissue adhesion and enhanced regeneration of skin structures in a mouse model without significant inflammation.
September 2025 in “Acta Biomaterialia” In this study, researchers developed injectable micropore-forming hydrogels that enhance tissue adhesion strength and promote wound healing by allowing better cell infiltration and inducing hair follicle regeneration in skin incision wound models.
4 citations
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October 2019 in “Journal of Dermatological Treatment” This study reported that injecting monofilament threads into the scalp significantly improved hair count and hair mass index in women with female pattern hair loss, with most participants noticing substantial improvements in hair characteristics compared to a placebo.
1 citations
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August 2024 in “Polymers” This study observed that dissolving microneedles made from PVP-K90 and HPMC E50, incorporating Oryza sativa L. extract complex, showed enhanced transfollicular skin penetration and maintained safety for keratinocytes, with the P25H5 formulation demonstrating faster dissolution and greater effectiveness.
March 2026 in “ACS Omega” This study reported that a novel hydrogel wound dressing, created using a Brachybotrys paridiformis polysaccharide derivative and chitosan, significantly accelerated wound healing and tissue regeneration in vivo, showing nearly complete healing by day 15 compared to controls.
November 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study introduced a novel scarless healing material called pgPE, made from a porous UHMWPE nanomembrane, and found that it promotes complete skin reconstruction and hair follicle regeneration by alleviating hypoxia and modulating immune responses to foster scar-free wound healing.
13 citations
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August 2022 in “Nanomaterials” This study reported that a novel trilayer electrospinning wound dressing can improve the wound microenvironment and accelerate repair in abdominal wall defects by facilitating directional biofluid transport and reducing inflammation.
60 citations
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March 2021 in “Bioactive Materials” This study found that nanofibrous membranes containing PNA nanogels enhanced wound healing in mice by modulating reactive oxygen species levels, improving cell adhesion and proliferation.
4 citations
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August 2023 in “Materials” This review highlights that synthetic biodegradable polymers like PVA, PCL, PLA, PLGA, PU, and PEO/PEG can address the limitations of natural polymers in wound healing, offering improved mechanical properties and slower degradation, thereby enhancing their application as wound dressings.
October 2025 in “Transplantation” This study developed dutasteride-loaded microneedle systems using a specific polymer to enhance transdermal delivery, demonstrating efficient drug release and increased accumulation in hair follicles, thus supporting their potential for treating androgenic alopecia.
1 citations
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December 2025 in “Journal of Investigative Dermatology” Photocrosslinkable biomaterials can improve wound healing by controlling mechanical environments.
17 citations
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August 2024 in “International Journal of Biological Macromolecules” The hydrogel dressings speed up healing and reduce scarring.
19 citations
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January 2020 in “Journal of Biophotonics” This study found that using a PEG-400/oleic acid mixture as an optical clearing agent enhanced the detection depth of particles in skin without causing dehydration, based on tests in rats and further testing in vivo.
March 2025 in “Frontiers in Pharmacology” This study developed a hydrogel dressing incorporating angelica polysaccharides, demonstrating enhanced wound healing properties in a mouse model by promoting rapid hemostasis, tissue healing, and new blood vessel formation compared to Tegaderm™ film.
7 citations
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January 2024 in “Regenerative Biomaterials” This study developed a multifunctional core-shell fiber dressing that preserves platelet-rich plasma for 180 days, facilitating sustained growth factor release and improved wound healing.
13 citations
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January 2024 in “Journal of Nanobiotechnology” This research reported that a newly developed adhesive wound dressing (SIS/PAA/LAP) demonstrated higher tissue adhesion and burst strength compared to conventional products, and improved tissue repair outcomes in animal models, suggesting potential for enhanced wound healing applications.
1 citations
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April 2025 in “Journal of Applied Polymer Science” This study found that microneedles based on polyphosphazene with green tea polyphenols significantly enhanced wound healing in a diabetic rat model.
2 citations
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May 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, hydrophilic EG7 PTK-UR foams promoted better wound healing and tissue integration in a porcine model compared to more hydrophobic PTK-UR variants and a polyester-based alternative, while matching a collagen-based standard.
21 citations
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January 2023 in “Biomaterials Science” This study investigated the use of dissolving microneedle patches to improve the skin-lightening effects of alpha-arbutin and resveratrol, finding that the patches enhanced intradermal delivery and slightly decreased the melanin index without affecting skin hydration or causing irritation over 24 hours.